Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

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http://www.wikidata.org/entity/Q36102775
β1 Integrins as Therapeutic Targets to Disrupt Hallmarks of CancerGIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells.Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease.The untapped potential of tyrosine-based G protein signaling.Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5.Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.The Gαi-GIV binding interface is a druggable protein-protein interactionBiochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin.Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein.MicroRNA expression profiling of intestinal mucosa tissue predicts multiple crucial regulatory molecules and signaling pathways for gut barrier dysfunction of AIDS patients.Cell Migration in Microfabricated 3D Collagen Microtracks is Mediated through the Prometastatic Protein Girdin.Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins
P2860

Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin

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http://www.wikidata.org/entity/Q36102775
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932