The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner
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Close encounters for the first time: Helicase interactions with DNA damageDiseases associated with defective responses to DNA damageRecognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion.Structure and Stability of Duplex DNA Containing (5′ S )-5′,8-Cyclo-2′-deoxyadenosine: An Oxidatively Generated Lesion Repaired by NERInsight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleasesMass spectrometry for the assessment of the occurrence and biological consequences of DNA adductsImpact of age-associated cyclopurine lesions on DNA repair helicases.Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1.Free radicals in chemical biology: from chemical behavior to biomarker development.A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βTranscriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Detection of oxidation products of 5-methyl-2'-deoxycytidine in Arabidopsis DNA.Radiation-induced formation of purine lesions in single and double stranded DNA: revised quantification.Comparison of mice with accelerated aging caused by distinct mechanismsOxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways.An ameliorative protocol for the quantification of purine 5',8-cyclo-2'-deoxynucleosides in oxidized DNA.Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η.Comprehensive Assessment of Oxidatively Induced Modifications of DNA in a Rat Model of Human Wilson's DiseaseSpatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellumDNA damage in normally and prematurely aged mice.Differences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes.Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induced DNA interstrand cross-links and monoadducts in mammalian cells.Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ.Induction of 8,5'-cyclo-2'-deoxyadenosine and 8,5'-cyclo-2'-deoxyguanosine in isolated DNA by Fenton-type reagentsIdentification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress.Aging on a different scale--chronological versus pathology-related aging.Epimeric 2-deoxyribose lesions: Products from the improper chemical repair of 2-deoxyribose radicals.Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems.DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation.Radiation-mediated formation of complex damage to DNA: a chemical aspect overview.Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody.Measurement of oxidatively induced DNA damage and its repair, by mass spectrometric techniques.Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.Purine 5',8-cyclo-2'-deoxynucleoside lesions: formation by radical stress and repair in human breast epithelial cancer cells.Replicative Bypass Studies of α-Anomeric Lesions of 2'-Deoxyribonucleosides in Vitro.Formation and repair of oxidatively generated damage in cellular DNA.
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P2860
The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@ast
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@en
type
label
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@ast
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@en
prefLabel
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@ast
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@en
P2093
P2860
P1433
P1476
The oxidative DNA lesions 8,5' ...... ng in a tissue-specific manner
@en
P2093
Cheryl L Clauson
Laura J Niedernhofer
Paul D Robbins
Yinsheng Wang
P2860
P304
P356
10.1111/J.1474-9726.2012.00828.X
P577
2012-05-22T00:00:00Z