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Substrate rigidity regulates human T cell activation and proliferation

Substrate rigidity regulates human T cell activation and proliferation

http://www.wikidata.org/entity/Q36106477

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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse Biophysical Aspects of T Lymphocyte Activation at the Immune Synapse Investigative and clinical applications of synthetic immune synapses Micro- and nanoscale engineering of cell signaling Linking form to function: Biophysical aspects of artificial antigen presenting cell design Mechanical regulation of T-cell functions Fighting the force: Potential of homeobox genes for tumor microenvironment regulation T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse CD28 and CD3 have complementary roles in T-cell traction forces.F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy Validation of reliable reference genes for real-time PCR in human umbilical vein endothelial cells on substrates with different stiffness.Nanoscale ligand spacing influences receptor triggering in T cells and NK cells The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility Human Primary Immune Cells Exhibit Distinct Mechanical Properties that Are Modified by Inflammation.Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.Lymph node biophysical remodeling is associated with melanoma lymphatic drainage.Synthesis of nanostructured and biofunctionalized water-in-oil droplets as tools for homing T cells Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility T cell antigen receptor activation and actin cytoskeleton remodeling.Adoptive immunotherapy for cancer.The extracellular matrix modulates the hallmarks of cancer.Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner.Improving T Cell Expansion with a Soft Touch.Mechanical Communication at the Immunological Synapse.T cell immunoengineering with advanced biomaterials.Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy.Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase.Surface engineering for lymphocyte programming.Substrate stiffness regulates B-cell activation, proliferation, class switch, and T-cell-independent antibody responses in vivo.Force and affinity in ligand discrimination by the TCR."Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse.Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity.Mechanotransduction Dynamics at the Cell-Matrix Interface.Substrate stiffness influences phenotype and function of human antigen-presenting dendritic cells.Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination.Phagocyte-extracellular matrix crosstalk empowers tumor development and dissemination.Receptor-mediated cell mechanosensing.

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P2860

Substrate rigidity regulates human T cell activation and proliferation

http://www.wikidata.org/entity/Q36106477

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

@zh

2012年论文

@zh-cn

name

Substrate rigidity regulates human T cell activation and proliferation

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Substrate rigidity regulates human T cell activation and proliferation

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type

label

Substrate rigidity regulates human T cell activation and proliferation

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Substrate rigidity regulates human T cell activation and proliferation

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prefLabel

Substrate rigidity regulates human T cell activation and proliferation

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Substrate rigidity regulates human T cell activation and proliferation

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JIMMUNOL.1102757

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Journal of Immunology

P1476

Substrate rigidity regulates human T cell activation and proliferation

@en

P2093

Keenan Bashour

http://www.w3.org/2001/XMLSchema#string

Keyue Shen

http://www.w3.org/2001/XMLSchema#string

Lance C Kam

http://www.w3.org/2001/XMLSchema#string

Michael C Milone

http://www.w3.org/2001/XMLSchema#string

Roddy S O'Connor

http://www.w3.org/2001/XMLSchema#string

Tatiana Akimova

http://www.w3.org/2001/XMLSchema#string

Wayne W Hancock

http://www.w3.org/2001/XMLSchema#string

Xueli Hao

http://www.w3.org/2001/XMLSchema#string

P2860

Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Adoptive T cell therapy for cancer in the clinic

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

Matrix elasticity directs stem cell lineage specification

Role of YAP/TAZ in mechanotransduction

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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1330-1339

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22732590

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3401283

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