Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
about
A small-cell lung cancer genome with complex signatures of tobacco exposureSequence variation in the Fanconi anemia gene FAAEnvironmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidenceGenomic sequencing in cancerGenomic impact of cigarette smoke, with application to three smoking-related diseasesGlobal methylation profiling of lung cancer identifies novel methylated genesTP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblastsEpigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature reviewAccurate DNA fragment sizing by capillary electrophoresis with laser-induced fluorescence array for detection of sequence specificity of DNA damageHigh-risk myelodysplastic syndromes and hypermethylation of the p15Ink4B gene.Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damageMolecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer.Lung cancer: a modified epigenome.DNA methylation and cancer.Molecular and genetic aspects of lung cancer.Lung cancer in never smokers: molecular profiles and therapeutic implications.The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells.Methylation levels at selected CpG sites in the factor VIII and FGFR3 genes, in mature female and male germ cells: implications for male-driven evolutionSpecific-mutational patterns of p53 gene in bladder transitional cell carcinoma among a group of Iraqi patients exposed to war environmental hazards.The role of genetics in the establishment and maintenance of the epigenome.Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase.A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database.Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA.Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis.Cytogenetics and molecular genetics of lung cancer.Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.A seven-gene CpG-island methylation panel predicts breast cancer progressionNoncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.Prenatal exposure to polycyclic aromatic hydrocarbons, benzo[a]pyrene-DNA adducts, and genomic DNA methylation in cord blood.CHEMICAL SELECTIVITY OF NUCLEOBASE ADDUCTION RELATIVE TO IN VIVO MUTATION SITES ON EXON 7 FRAGMENT OF P53 TUMOR SUPPRESSOR GENESomatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbonsMethylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.Effect of CpG methylation at different sequence context on acrolein- and BPDE-DNA binding and mutagenesisAn intercalation inhibitor altering the target selectivity of DNA damaging agents: synthesis of site-specific aflatoxin B1 adducts in a p53 mutational hotspot.Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.
P2860
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P2860
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@ast
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@en
type
label
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@ast
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@en
prefLabel
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@ast
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@en
P2093
P2860
P356
P1476
Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
@en
P2093
G P Pfeifer
M F Denissenko
P2860
P304
P356
10.1073/PNAS.94.8.3893
P407
P577
1997-04-01T00:00:00Z