Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis
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Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infectionsChemical and Structural Insights into the Regioversatility of the Aminoglycoside Acetyltransferase EisPotent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosisInhibition of aminoglycoside 6'-N-acetyltransferase type Ib by zinc: reversal of amikacin resistance in Acinetobacter baumannii and Escherichia coli by a zinc ionophoreNew trends in aminoglycosides use.Inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular docking.Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal salts.Identification of an Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase type Ib [AAC(6')-Ib] by Glide Molecular DockingInhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithione.Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition.Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis.Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilisMechanisms of Resistance to Aminoglycoside Antibiotics: Overview and PerspectivesUnexpected N-acetylation of capreomycin by mycobacterial Eis enzymes.A review of patents (2011-2015) towards combating resistance to and toxicity of aminoglycosidesRise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm.Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis.Comparative Study of Eis-like Enzymes from Pathogenic and Nonpathogenic Bacteria.Understanding and overcoming aminoglycoside resistance caused by N-6'-acetyltransferase.Advances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology.Resistance in tuberculosis: what do we know and where can we go?Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis.Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis.Expanding Aminoglycoside Resistance Enzyme Regiospecificity by Mutation and Truncation.6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes.Generation of α-Iminyl Radicals from α-Bromo Cyclic N-Sulfonylimines and Application to Coupling with Various Radical Acceptors Using a Photoredox Catalyst.Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight.Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities.Evaluation of Aminoglycoside and Carbapenem Resistance in a Collection of Drug-Resistant Pseudomonas aeruginosa Clinical Isolates.Amikacin: Uses, Resistance, and Prospects for Inhibition.Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3'--phosphotransferase type IIaThe Role of Antibiotic-Target-Modifying and Antibiotic-Modifying Enzymes in Drug Resistance
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P2860
Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Identification and characteriz ...... rom Mycobacterium tuberculosis
@ast
Identification and characteriz ...... rom Mycobacterium tuberculosis
@en
type
label
Identification and characteriz ...... rom Mycobacterium tuberculosis
@ast
Identification and characteriz ...... rom Mycobacterium tuberculosis
@en
prefLabel
Identification and characteriz ...... rom Mycobacterium tuberculosis
@ast
Identification and characteriz ...... rom Mycobacterium tuberculosis
@en
P2860
P356
P1433
P1476
Identification and characteriz ...... rom Mycobacterium tuberculosis
@en
P2093
Keith D Green
Wenjing Chen
P2860
P356
10.1002/CMDC.201100332
P577
2011-09-05T00:00:00Z