Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence.
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Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animalsOrexin antagonists for neuropsychiatric disease: progress and potential pitfallsThe neurobiology of modafinil as an enhancer of cognitive performance and a potential treatment for substance use disorders.Orexin/hypocretin role in reward: implications for opioid and other addictionsHypocretin/Orexin regulation of dopamine signaling and cocaine self-administration is mediated predominantly by hypocretin receptor 1.Smoking, Alcohol, Drug Use, Abuse and Dependence in Narcolepsy and Idiopathic Hypersomnia: A Case-Control StudyThe highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.The hypocretins and the reward function: what have we learned so far?Voluntary Sleep Loss in Rats.Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight loss.Nicotinic receptors regulate the dynamic range of dopamine release in vivoOrexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use.Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism.Hypocretins, Neural Systems, Physiology, and Psychiatric Disorders.Methamphetamine addiction: involvement of CREB and neuroinflammatory signaling pathways.Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner.How contexts promote and prevent relapse to drug seeking.Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse.Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats.Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats.Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine.A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?Global analysis of gene expression mediated by OX1 orexin receptor signaling in a hypothalamic cell line.Orexin/Hypocretin System: Role in Food and Drug Overconsumption.Assessment of the abuse liability of a dual orexin receptor antagonist: a crossover study of almorexant and zolpidem in recreational drug users.Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine.The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders.Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats.The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.
P2860
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P2860
Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@ast
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@en
type
label
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@ast
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@en
prefLabel
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@ast
Hypocretin-1 receptors regulat ...... behavioral genetics evidence.
@en
P2093
P2860
P356
P1476
Hypocretin-1 receptors regulat ...... d behavioral genetics evidence
@en
P2093
Jonathan A Hollander
Paul J Kenny
P2860
P356
10.3389/FNBEH.2012.00047
P577
2012-07-24T00:00:00Z