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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

http://www.wikidata.org/entity/Q36119247

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Mathematics in modern immunology Reconciling Estimates of Cell Proliferation from Stable Isotope Labeling Experiments A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations.Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels.Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches.How many TCR clonotypes does a body maintain?Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice.Quantifying T lymphocyte turnover.Which of our modeling predictions are robust?Dynamical and Mechanistic Reconstructive Approaches of T Lymphocyte Dynamics: Using Visual Modeling Languages to Bridge the Gap between Immunologists, Theoreticians, and Programmers.Stochastic descriptors to study the fate and potential of naive T cell clonotypes in the periphery.Predicting CD4 T-Cell Reconstitution Following Pediatric Hematopoietic Stem Cell Transplantation.Mathematical modeling of oncogenesis control in mature T-cell populations.Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness

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P2860

Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

http://www.wikidata.org/entity/Q36119247

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Journal of the Royal Society Interface

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Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

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Rob J De Boer

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P2860

Lymphocyte kinetics: the interpretation of labelling data.

Quantifying cell turnover using CFSE data.

Explicit kinetic heterogeneity: mathematical models for interpretation of deuterium labeling of heterogeneous cell populations.

Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients.

Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells

Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.

In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection.

Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo.

Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: studies in vitro, in animals, and in humans.

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2191-2200

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scholarly article

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10.1098/RSIF.2012.0149

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74

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9

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Alan S. Perelson

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2012-04-18T00:00:00Z

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224708323

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22513720

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3405764

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