The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways
about
Guidance molecules in synapse formation and plasticityMechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersActivity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrinsSynaptic cell adhesionThe Role of Ephs and Ephrins in Memory FormationEphA receptor signaling--complexity and emerging themesMolecular mechanisms of dendrite stabilityCrystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 ReceptorSynaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formationEphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomersThe SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein CasRetinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion.Intercellular protein-protein interactions at synapses.Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex.Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease.Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations.Stress-induced lipocalin-2 controls dendritic spine formation and neuronal activity in the amygdala.Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats.Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation.The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells.Integrins modulate relapse to cocaine-seeking.EphA signaling promotes actin-based dendritic spine remodeling through slingshot phosphatase.Regional Regulation of Purkinje Cell Dendritic Spines by Integrins and Eph/Ephrins.ECM receptors in neuronal structure, synaptic plasticity, and behavior.Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude miceDistinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor.The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting.Eph/ephrin signaling: networks.Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinomaPromotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.Improving RPE adhesion to Bruch's membrane.Bidirectional signaling of ErbB and Eph receptors at synapses.Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling.Retinal pigment epithelium differentiation of stem cells: current status and challenges.Regulation of axonal outgrowth and pathfinding by integrin-ECM interactions.Casting a net on dendritic spines: the extracellular matrix and its receptors.Eph receptors and ephrins in neuron-astrocyte communication at synapses.
P2860
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P2860
The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@ast
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@en
type
label
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@ast
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@en
prefLabel
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@ast
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@en
P2093
P2860
P356
P1476
The EphA4 receptor regulates d ...... a1-integrin signaling pathways
@en
P2093
Caroline Bourgin
Elena B Pasquale
Keith K Murai
Melanie Richter
P2860
P304
P356
10.1083/JCB.200610139
P407
P577
2007-09-17T00:00:00Z