Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation
about
Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart.WDR23 regulates NRF2 independently of KEAP1.Potential therapeutic action of nitrite in sickle cell diseaseNonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice.Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease.Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression.Emerging point-of-care technologies for sickle cell disease screening and monitoring.CDDO and Its Role in Chronic Diseases.An overview of the mechanisms and novel roles of Nrf2 in cardiovascular diseases.Heme as a Target for Therapeutic Interventions.Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function.Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model.Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice.Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease.Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.Podocytes are new cellular targets of haemoglobin-mediated renal damage.Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.Developing new pharmacotherapeutic approaches to treating sickle-cell disease.Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate.Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease
P2860
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P2860
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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2015年论文
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2015年论文
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name
Amelioration of inflammation a ...... model mice by Nrf2 activation
@ast
Amelioration of inflammation a ...... model mice by Nrf2 activation
@en
type
label
Amelioration of inflammation a ...... model mice by Nrf2 activation
@ast
Amelioration of inflammation a ...... model mice by Nrf2 activation
@en
prefLabel
Amelioration of inflammation a ...... model mice by Nrf2 activation
@ast
Amelioration of inflammation a ...... model mice by Nrf2 activation
@en
P2093
P2860
P356
P1476
Amelioration of inflammation a ...... model mice by Nrf2 activation
@en
P2093
Akihito Otsuki
Eriko Naganuma
James Douglas Engel
Kouhei Tsuchida
Makiko Hayashi
Masayuki Yamamoto
Masue Imaizumi
Mikiko Suzuki
Nadine Keleku-Lukwete
Osamu Tanabe
P2860
P304
12169-12174
P356
10.1073/PNAS.1509158112
P407
P577
2015-09-14T00:00:00Z