A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex
about
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interactionCrystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATAStructural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domainsStructural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1G1n3p is capable of binding to UAS(NTR) elements and activating transcription in Saccharomyces cerevisiae.Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factorYoung Investigator Award Lecture. Structures of larger proteins, protein-ligand and protein-DNA complexes by multidimensional heteronuclear NMR.Substitution of DNA-contacting amino acids with functional variants in the Gata-1 zinc finger: a structurally and phylogenetically guided mutagenesisThe N-terminal fingers of chicken GATA-2 and GATA-3 are independent sequence-specific DNA binding domainsA nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes.The two zinc finger-like domains of GATA-1 have different DNA binding specificitiesThe zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1.The evolutionary duplication and probable demise of an endodermal GATA factor in Caenorhabditis elegans.Cysteine-rich LIM domains of LIM-homeodomain and LIM-only proteins contain zinc but not iron.Recognition of specific nucleotide bases and cooperative DNA binding by the trans-acting nitrogen regulatory protein NIT2 of Neurospora crassaEscherichia coli topoisomerase I is an iron and zinc binding protein.Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles.The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domainRole of the GATA family of transcription factors in andrology.Direct analysis of native and chimeric GATA specific DNA binding proteins from Aspergillus nidulansNuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by GlutamineFunctional analysis of transcription factor binding sites in human promoters.Homotypic interactions of chicken GATA-1 can mediate transcriptional activationIron chelators with topoisomerase-inhibitory activity and their anticancer applications.elt-2, a second GATA factor from the nematode Caenorhabditis elegans.urbs1, a gene regulating siderophore biosynthesis in Ustilago maydis, encodes a protein similar to the erythroid transcription factor GATA-1.Human nucleotide excision repair protein XPA: 1H NMR and CD solution studies of a synthetic peptide fragment corresponding to the zinc-binding domain (101-141).A member of a novel family of yeast 'zn-finger' proteins mediates the transition from stationary phase to cell proliferation.The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding.Human GATA-3 trans-activation, DNA-binding, and nuclear localization activities are organized into distinct structural domains.Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal.Cu(I) Disrupts the Structure and Function of the Nonclassical Zinc Finger Protein Tristetraprolin (TTP).The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys2-His2 zinc finger motif.Structures of protein complexes by multidimensional heteronuclear magnetic resonance spectroscopy.Regulation of J6 gene expression by transcription factor GATA-4.Expression of a Drosophila GATA transcription factor in multiple tissues in the developing embryos. Identification of homozygous lethal mutants with P-element insertion at the promoter region.Evidence that highly conserved residues of transmembrane segment 6 of Escherichia coli MntH are important for transport activity.Analysis, by electrospray ionization mass spectrometry, of several forms of Clostridium pasteurianum rubredoxin.Alteration of zif268 zinc-finger motifs gives rise to non-native zinc-co-ordination sites but preserves wild-type DNA recognition.
P2860
Q24310787-E89E49DD-8D41-41C7-A323-3D12C16DA3C6Q27651158-A1F5CA75-B182-4DC9-8559-777F797369FBQ27653179-DCCFCB11-A646-4062-9B5B-45E6AE41EB06Q27671779-5DF8AAA4-C76E-41FB-8D34-F5A740C78647Q27940307-3FFCA99C-E2E2-465D-84A2-222CAF8EC2C8Q28505571-37DE6E30-D3AA-4737-85AB-9AE51D387BE5Q30420419-577CCFF6-CA09-47A0-A615-6BDA0FC2B973Q33323118-ABD8D7C4-0F60-47AC-ACFD-3597D0509F87Q33886687-3810E366-0CED-454D-B51A-3396719E2D3CQ34025068-2D72B0CC-AD80-4718-838F-F9D9E170C76EQ34064513-21A1A61D-701C-47D2-BFD1-42287BA77227Q34066369-B669AA55-7E9B-422A-8C6F-8D1E016C1AF5Q34318281-277AA946-1FEF-486D-9465-D1387BB03664Q34618765-E9F94175-980E-4726-B178-15FF80B3EF96Q34950802-FA44717D-65C2-4D45-BAFC-EA8C581ABA54Q34998584-D154106D-56E9-47D0-A848-0FC4354B9196Q35068744-FC7C5548-D760-4BAC-B959-183ED67D2EB3Q35127556-C37C0DFF-4845-495B-8AE1-A10CE17385AFQ35515561-5054364F-EA4F-4489-A03D-4E439E8D8BACQ35821075-A60086E6-B4D6-41CB-886A-29DF123622D9Q35873516-292DF3F0-12E3-4344-8A4E-C0823AB683CFQ36291459-28F861F6-5F24-4422-890D-65316D283DB6Q36378033-2CA8BA89-CF0D-4EAC-AF2B-8EA07AD3A859Q36549797-E0FA2E30-0D68-44A7-955B-14EF897B3007Q36568915-6BCABA8F-2D69-44DC-A387-35557F3E7CD5Q36707679-A8F4BC7E-E95C-498C-826F-06CD99D479E4Q36826150-6E18B5A6-48A0-408E-9D18-2B4E7D640988Q36867138-F6FBAFC0-5078-43FF-9169-07E9811BB7C9Q37635488-1C119DFE-ED79-4787-B2B4-771C94165FF0Q37677517-89A8C011-C940-445E-AA03-E10C98C3D2E8Q38310615-D5BF195A-0BE7-4CF5-9125-7E1A3E824B8FQ38349215-E66924AE-1E8D-4786-A21C-EB1D6A4730D5Q38756757-28196A80-FBE1-4E5F-84DC-FADE2DF9BB95Q39687327-5CCBEB8F-9675-49D4-A7F6-F2D618FF7931Q40954112-72FF33D4-B4D7-4B29-9AD6-BEEB125A7FA8Q41354071-AE051892-F602-45EA-9597-CCF410626E96Q42676592-F7820482-24E7-423E-8108-21E831D355FAQ42735766-F529F2AD-BC52-4188-BB95-98379F9EE1E5Q42832018-3385C748-9400-48C2-A6A1-FE644D334213Q42991010-E820CD53-642D-412B-8D9E-24C8E6DF390F
P2860
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@ast
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@en
type
label
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@ast
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@en
prefLabel
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@ast
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@en
P2093
P2860
P356
P1476
A small single-"finger" peptid ...... DNA as a zinc or iron complex
@en
P2093
G Felsenfeld
J G Omichinski
P2860
P304
P356
10.1073/PNAS.90.5.1676
P407
P577
1993-03-01T00:00:00Z