Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria.
about
Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trialsPrediction of Improved Antimalarial Chemoprevention with Weekly Dosing of Dihydroartemisinin-Piperaquine.Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection.Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trialPiperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean womenEx vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to ThailandPiperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia.Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers.Prevention and control of malaria in pregnancy - new threats, new opportunities?Single dose treatment of malaria - current status and perspectives.Challenges to replace ACT as first-line drug.The application of physiologically-based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy.A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malComparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy.Drugs in Development for Malaria.
P2860
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P2860
Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@ast
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@en
type
label
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@ast
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@en
prefLabel
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@ast
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@en
P2093
P2860
P356
P1476
Evaluation of the QT effect of ...... ment of uncomplicated malaria.
@en
P2093
Bart Laurijssens
Borje Darpo
Fiona Macintyre
Georg Ferber
Peter Siegl
Stephan Duparc
Stephen Toovey
P2860
P304
P356
10.1111/BCP.12680
P407
P577
2015-05-13T00:00:00Z