The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide.
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Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic PropertiesPhotoinduced release of nitroxyl and nitric oxide from diazeniumdiolatesH2S and its role in redox signaling.Isopropylamine NONOate (IPA/NO) moderates neointimal hyperplasia following vascular injuryNitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling.Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.Nitrosyl hydride (HNO) replaces dioxygen in nitroxygenase activity of manganese quercetin dioxygenaseGrignard reagent-mediated conversion of an acyl nitroso-anthracene cycloadduct to a nitrone.Ring expansions of acyloxy nitroso compoundsSulfur as a signaling nutrient through hydrogen sulfide.The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NORecent advances in the chemical biology of nitroxyl (HNO) detection and generation.The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troublesIdentification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method.The effects of nitroxyl (HNO) on H₂O₂ metabolism and possible mechanisms of HNO signaling.The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidationNitrosyl hydride (HNO) as an O2 analogue: long-lived HNO adducts of ferrous globins.Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling.Angeli's Salt, a nitroxyl anion donor, reverses endothelin-1 mediated vascular dysfunction in murine aorta.HNO/NO Conversion Mechanisms of Cu-Based HNO Probes with Implications for Cu,Zn-SOD.The chemical biology of HNO signaling.A fast-response, highly sensitive and selective fluorescent probe for the ratiometric imaging of nitroxyl in living cells.Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex.Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols.The chemical biology of protein hydropersulfides: Studies of a possible protective function of biological hydropersulfide generation.A selective phosphine-based fluorescent probe for nitroxyl in living cells.Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses.Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C.Comparison of Reductive Ligation-Based Detection Strategies for Nitroxyl (HNO) and S-Nitrosothiols.Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine.Modeling of S-Nitrosothiol-Thiol Reactions of Biological Significance: HNO Production by S-Thiolation Requires a Proton Shuttle and Stabilization of Polar Intermediates.Oxygen metabolism by neuronal nitric-oxide synthase.A chemiluminescent probe for cellular peroxynitrite using a self-immolative oxidative decarbonylation reaction.
P2860
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P2860
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@ast
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@en
type
label
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@ast
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@en
prefLabel
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@ast
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@en
P2093
P356
P1476
The physiological chemistry an ...... and enigmatic nitrogen oxide.
@en
P2093
Andrew S Dutton
David A Wink
Jon M Fukuto
Michael D Bartberger
Nazareno Paolocci
P304
P356
10.1021/TX0496800
P50
P577
2005-05-01T00:00:00Z