The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells
about
Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerReceptor tyrosine kinases in the nucleusSimultaneous profiling of 194 distinct receptor transcripts in human cellsProtein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal CancerProteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.Matrix metalloproteinases - From the cleavage data to the prediction tools and beyond.The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)PTK 7 is a transforming gene and prognostic marker for breast cancer and nodal metastasis involvement.Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth.Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.Therapeutic Targeting of PTK7 is Cytotoxic in Atypical Teratoid Rhabdoid Tumors.Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells.Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma.Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases.Antibody-drug conjugate targeting protein tyrosine kinase 7, a receptor tyrosine kinase-like molecule involved in WNT and vascular endothelial growth factor signaling: effects on cancer stem cells, tumor microenvironment and whole-body homeostasis.Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.Genome-wide screen of gamma-secretase-mediated intramembrane cleavage of receptor tyrosine kinases.Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.PTK6 Localized at the Plasma Membrane Promotes Cell Proliferation and MigratiOn Through Phosphorylation of Eps8.miR‑205‑5p/PTK7 axis is involved in the proliferation, migration and invasion of colorectal cancer cells.
P2860
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P2860
The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The cytosolic domain of protei ...... igration in colon cancer cells
@ast
The cytosolic domain of protei ...... igration in colon cancer cells
@en
type
label
The cytosolic domain of protei ...... igration in colon cancer cells
@ast
The cytosolic domain of protei ...... igration in colon cancer cells
@en
prefLabel
The cytosolic domain of protei ...... igration in colon cancer cells
@ast
The cytosolic domain of protei ...... igration in colon cancer cells
@en
P2860
P50
P356
P1476
The cytosolic domain of protei ...... igration in colon cancer cells
@en
P2093
Hye-Won Na
P2860
P304
25001-25009
P356
10.1074/JBC.M112.348904
P407
P577
2012-06-04T00:00:00Z