Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
about
Next-generation mammalian genetics toward organism-level systems biologyCRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.Genome Editing with CRISPR-Cas9: Can It Get Any Better?Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth.Maternal Supply of Cas9 to Zygotes Facilitates the Efficient Generation of Site-Specific Mutant Mouse Models.CRISPRs for Optimal Targeting: Delivery of CRISPR Components as DNA, RNA, and Protein into Cultured Cells and Single-Cell Embryos.Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA RatsSuccessful correction of hemophilia by CRISPR/Cas9 genome editing in vivo: delivery vector and immune responses are the key to success.Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair.Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote.Efficient gene targeting in mouse zygotes mediated by CRISPR/Cas9-protein.A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes.Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation.Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors.Production of knock-in mice in a single generation from embryonic stem cells.Tuning CRISPR-Cas9 Gene Drives in Saccharomyces cerevisiae.Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins.Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes.An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing.CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion
P2860
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P2860
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@ast
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@en
type
label
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@ast
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@en
prefLabel
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@ast
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@en
P2093
P2860
P50
P356
P1433
P1476
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
@en
P2093
Alexandre Fraichard
Alison Crénéguy
Carine Giovannangeli
Charlotte Boix
Claire Usal
Ignacio Anegon
Laurent Tesson
Lucas Brusselle
Reynald Thinard
Sandra Fontanière
P2860
P2888
P356
10.1038/SREP14410
P407
P577
2015-10-07T00:00:00Z