Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.
about
Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope GlycoproteinReducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP TrimersEffects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction.Progress toward active or passive HIV-1 vaccination.Native-like Env trimers as a platform for HIV-1 vaccine design.Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoproteinAdjuvants: tailoring humoral immune responses.Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers.Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers.Immunogenicity in rabbits of SOSIP trimers from clades A, B and C, given individually, sequentially or in combinations.Neutralization tiers of HIV-1.Exploiting glycan topography for computational design of Env glycoprotein antigenicity.The Hard Way towards an Antibody-Based HIV-1 Env Vaccine: Lessons from Other Viruses.Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.Molecular basis of unusually high neutralization resistance in tier 3 HIV-1 strain 253-11.Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies.Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro.Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization BreadthStabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodiesStrategies for a multi-stage neutralizing antibody-based HIV vaccineRational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope TrimersElectron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization
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P2860
Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@ast
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@en
type
label
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@ast
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@en
prefLabel
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@ast
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@en
P2093
P2860
P1433
P1476
Sequential and Simultaneous Im ...... rimers from Clades A, B and C.
@en
P2093
Albert Cupo
Andrew B Ward
Celia C LaBranche
Gabriel Ozorowski
Ian A Wilson
John P Moore
Kelly K Lee
Michael Golabek
Miklos Guttman
P J Klasse
P2860
P304
P356
10.1371/JOURNAL.PPAT.1005864
P577
2016-09-14T00:00:00Z