PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation - Wikidata - wikimedia - TriplyDB

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

http://www.wikidata.org/entity/Q36138617

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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation A general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativity GATA-1 associates with and inhibits p53.PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells Molecular ties between the cell cycle and differentiation in embryonic stem cells.A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.A Comprehensive Profile of ChIP-Seq-Based PU.1/Spi1 Target Genes in Microglia Transcriptional control of erythropoiesis: emerging mechanisms and principles.Reprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.MAPK-mediated phosphorylation of GATA-1 promotes Bcl-XL expression and cell survival.Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1.Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter.A network of genes antagonistic to the LIN-35 retinoblastoma protein of Caenorhabditis elegans.At the crossroads: diverse roles of early thymocyte transcriptional regulators.Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors.H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation.High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.Mi2beta shows chromatin enzyme specificity by erasing a DNase I-hypersensitive site established by ACF.Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles Spi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells.Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.The RB/E2F pathway and regulation of RNA processing Ski negatively regulates erythroid differentiation through its interaction with GATA1.Epigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine.The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis.Proteomics approaches for myeloid leukemia drug discovery.Concise review: erythroid versus myeloid lineage commitment: regulating the master regulators.E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding.The RB tumor suppressor at the intersection of proliferation and immunity: relevance to disease immune evasion and immunotherapy.PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.Point mutations in two EVI1 Zn fingers abolish EVI1-GATA1 interaction and allow erythroid differentiation of murine bone marrow cells.Transcriptional regulation of Elf-1: locus-wide analysis reveals four distinct promoters, a tissue-specific enhancer, control by PU.1 and the importance of Elf-1 downregulation for erythroid maturation GFI1B controls its own expression binding to multiple sites.

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P2860

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

http://www.wikidata.org/entity/Q36138617

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

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PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

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type

label

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

@ast

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

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prefLabel

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

@ast

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

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MCB.23.21.7460-7474.2003

P1433

Molecular and Cellular Biology

P1476

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation

@en

P2093

Arthur I Skoultchi

http://www.w3.org/2001/XMLSchema#string

Igor Matushansky

http://www.w3.org/2001/XMLSchema#string

Kevin S Choe

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Natasha Rekhtman

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Stuart Murray

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Tomas Stopka

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P2860

hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation

Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1

Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction

Induction of cyclin D1 by simian virus 40 small tumor antigen

A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

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7460-7474

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scholarly article

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10.1128/MCB.23.21.7460-7474.2003

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21

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23

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2003-11-01T00:00:00Z

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14559995

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207581

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