Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).
about
MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathwayThrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cellsThe Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor EnvironmentExtracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal DomainLow thrombospondin 2 expression is predictive of low tumor regression after neoadjuvant chemoradiotherapy in rectal cancer.CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis.E2F-1 directly regulates thrombospondin 1 expression.Zinc finger gene 217 (ZNF217) Promoted Ovarian Hyperstimulation Syndrome (OHSS) through Regulating E2 Synthesis and Inhibiting Thrombospondin-1 (TSP-1).Extracellular matrix, inflammation, and the angiogenic response.Low level of low-density lipoprotein receptor-related protein 1 predicts an unfavorable prognosis of hepatocellular carcinoma after curative resection.p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancersDown regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancerThrombospondin-1 inhibits VEGF receptor-2 signaling by disrupting its association with CD47.Disruption of thrombospondin-2 accelerates ischemic fracture healing.Expression of angiogenic basic fibroblast growth factor, platelet derived growth factor, thrombospondin-1 and their receptors at the porcine maternal-fetal interface.Chronic delivery of a thrombospondin-1 mimetic decreases skeletal muscle capillarity in miceDNA methylation profile distinguishes clear cell sarcoma of the kidney from other pediatric renal tumorsLong-term gene therapy with thrombospondin 2 inhibits TGF-β activation, inflammation and angiogenesis in chronic allograft nephropathyThe thrombospondins.Molecular mechanisms of enhancing porcine granulosa cell proliferation and function by treatment in vitro with anti-inhibin alpha subunit antibody.The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2.ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer.Identification of TAX2 peptide as a new unpredicted anti-cancer agent.Physiological Capillary Regression is not Dependent on Reducing VEGF Expression.Thrombospondin-1 and pigment epithelium-derived factor enhance responsiveness of KM12 colon tumor to metronomic cyclophosphamide but have disparate effects on tumor metastasis.Thrombospondin-based antiangiogenic therapy.Thrombospondins in cancer.Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF.LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studiesChronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes.Thrombospondin and apoptosis: molecular mechanisms and use for design of complementation treatments.Pregnancy-associated genes contribute to antiluteolytic mechanisms in ovine corpus luteum.The mammalian ovary from genesis to revelation.The interaction of Thrombospondins with extracellular matrix proteins.The role of thrombospondins in wound healing, ischemia, and the foreign body reaction.Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico InvestigationThe thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis.Therapies using anti-angiogenic peptide mimetics of thrombospondin-1.
P2860
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P2860
Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@ast
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@en
type
label
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@ast
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@en
prefLabel
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@ast
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@en
P2093
P2860
P356
P1476
Thrombospondin-1 inhibits VEGF ...... tor-related protein-1 (LRP-1).
@en
P2093
Jack Lawler
James Greenaway
Jim Petrik
Jonathan Lamarre
Paul Bornstein
Roger Moorehead
P2860
P304
P356
10.1002/JCP.20904
P577
2007-03-01T00:00:00Z