Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation - Wikidata - wikimedia - TriplyDB

Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

http://www.wikidata.org/entity/Q36141531

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Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 Role of Nrf2 in oxidative stress and toxicity Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia.Potential Use of Chemoprotectants against the Toxic Effects of Cyanotoxins: A Review.Electrophilic tuning of the chemoprotective natural product sulforaphane.Sulforaphane inhibits TNF-α-induced adhesion molecule expression through the Rho A/ROCK/NF-κB signaling pathway.Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening.Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol.The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses.Dietary broccoli mildly improves neuroinflammation in aged mice but does not reduce lipopolysaccharide-induced sickness behavior Precise determination of the erythema response of human skin to ultraviolet radiation and quantification of effects of protectors Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effe Targeting mutant p53 shows promise for sunscreens and skin cancer The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress.Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma.Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway.Two Novel Flavin-Containing Monooxygenases Involved in Biosynthesis of Aliphatic Glucosinolates.Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer.Preparation of Disubstituted Phenyl Propargyl Alcohols, their Use in Oxathiolene Oxide Synthesis, and Evaluation of the Oxathiolene Oxide Products as Anticarcinogenic Enzyme Inducers.Stability of sulforaphane for topical formulation.Oxidative stress mediates chemical hypoxia-induced injury and inflammation by activating NF-κb-COX-2 pathway in HaCaT cells.The effects of topically applied glycolic acid and salicylic acid on ultraviolet radiation-induced erythema, DNA damage and sunburn cell formation in human skin.Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin Natural agents: cellular and molecular mechanisms of photoprotection.The cytoprotective role of the Keap1-Nrf2 pathway.Natural products as photoprotection.The role of transcription factor Nrf2 in skin cells metabolism.What do we know about sulforaphane protection against photoaging?Phytochemicals for the Prevention of Photocarcinogenesis.Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin.The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress.Enriching Glucoraphanin in Brassica rapa Through Replacement of BrAOP2.2/BrAOP2.3 with Non-functional Genes Sulforaphane exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia.

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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2007 nî lūn-bûn

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Proceedings of the National Academy of Sciences of the United States of America

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Albena T Dinkova-Kostova

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Andrea L Benedict

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Christine Min

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Jed W Fahey

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Paul Talalay

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Scott L Wehage

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Zachary R Healy

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P2860

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

Myeloperoxidase: friend and foe

Piecing together the puzzle of cutaneous mosaicism.

Identification of polymorphic antioxidant response elements in the human genome.

Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer.

UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients.

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants.

Cutaneous squamous-cell carcinoma.

Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice

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104

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5888799

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17956979

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2077285

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