Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+-Glucose Cotransport.
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Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal InjuryHuman amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo.Sodium Glucose Cotransporter-2 Inhibition in Heart Failure: Potential Mechanisms, Clinical Applications, and Summary of Clinical Trials.Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects.Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation.Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits.The Role of Sodium in Diabetic CardiomyopathyMyocyte [Na] Dysregulation in Heart Failure and Diabetic Cardiomyopathy
P2860
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P2860
Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+-Glucose Cotransport.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@ast
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@en
type
label
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@ast
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@en
prefLabel
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@ast
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@en
P2093
P2860
P356
P1476
Intracellular Na+ Concentratio ...... anced Na+-Glucose Cotransport.
@en
P2093
Florin Despa
Kenneth B Margulies
Rebekah Lambert
Sanda Despa
Sarah Srodulski
Xiaoli Peng
P2860
P304
P356
10.1161/JAHA.115.002183
P577
2015-08-27T00:00:00Z