MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV - Wikidata - wikimedia - TriplyDB

MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

http://www.wikidata.org/entity/Q36142477

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Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions.Immunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivo Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer Gene Therapy for Duchenne muscular dystrophy.Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors Immune responses to AAV vectors: overcoming barriers to successful gene therapy Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies Copackaging of multiple adeno-associated viral vectors in a single production step.Complexity of immune responses to AAV transgene products - Example of factor IX.Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer.Unraveling the complex story of immune responses to AAV vectors trial after trial.In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice.Adeno-Associated Viral Vectors at the Frontier between Tolerance and Immunity.Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors.Emerging Issues in AAV-Mediated In Vivo Gene Therapy.Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway.

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

http://www.wikidata.org/entity/Q36142477

description

2012 nî lūn-bûn

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2012年论文

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name

MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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Molecular Therapy

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MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

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Anne Galy

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Christine Le Bec

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David Alexandre Gross

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Florence Boisgérault

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Léa Brault

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Muriel Sudres

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Sylvie Da Rocha

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Séverine Ciré

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Virginie Vasseur

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Véronique Blouin

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P2860

Functional role of type I and type II interferons in antiviral defense

Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism.

Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Gout-associated uric acid crystals activate the NALP3 inflammasome

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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1571-1581

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scholarly article

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10.1038/MT.2012.101

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8

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20

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Bernhard Ryffel

Véronique Blouin

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2012-05-29T00:00:00Z

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225073142

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22643865

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3412489

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