Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.
about
PEGylated Adenoviruses: From Mice to MonkeysLiver-targeted gene therapy: Approaches and challengesGutless adenovirus: last-generation adenovirus for gene therapyCo-expression of sCD40LIg and CTLA4Ig mediated by adenovirus prolonged mouse skin allograft survival.Engineering viral vectors to subvert the airway defense response.Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII miceStrategies to modulate immune responses: a new frontier for gene therapyCombinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles.Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administrationSuccessful readministration of adeno-associated virus vectors to the mouse lung requires transient immunosuppression during the initial exposureExpression of herpes simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes.Implication of interfering antibody formation and apoptosis as two different mechanisms leading to variable duration of adenovirus-mediated transgene expression in immune-competent mice.Ovine adenovirus vectors overcome preexisting humoral immunity against human adenoviruses in vivoAdenovirus-mediated gene expression in vivo is enhanced by the antiapoptotic bcl-2 gene.Role of CD28/CD80-86 and CD40/CD154 costimulatory interactions in host defense to primary herpes simplex virus infection."Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lungHepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection.Existing antilisterial immunity does not inhibit the development of a Listeria monocytogenes-specific primary cytotoxic T-lymphocyte response.Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.AAV-mediated gene transfer for hemophilia.Oral adenoviral-based vaccines: historical perspective and future opportunity.Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice.Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy.Immune responses to adeno-associated virus and its recombinant vectors.Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials.Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advancesImmunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A miceGene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategiesLiver gene therapy: advances and hurdles.In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectorsImproving adenovirus based gene transfer: strategies to accomplish immune evasion.Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review.Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liverCardiac gene therapy: are we there yet?Gene therapy for lung cancer malignant pleural effusion: current and future nano-biotechnology.Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure.Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactionsSuccessful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors.Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene.
P2860
Q24635276-1677FC49-C633-4F20-A676-AD242ADD94C5Q28085748-1EC3250E-A961-4360-A24A-9C0B4F09E757Q28277560-3AA62563-7D13-46F6-8CF5-C8701A6EAED0Q33243196-C263368D-5F64-4F68-BFA7-E20C99D9956AQ33643006-BC4C7537-CA7D-4461-B7F2-597CD658E34CQ33645370-8CADEEFB-FA43-4D83-983D-380F677D826CQ33713999-AAFBE9F9-E464-4F33-89F7-0A59458FAEE4Q33783905-7C3CDD86-E04B-435F-AC5E-A790A7DD1833Q33783991-9C5CB923-5C26-48F4-B8BC-E3B118759E42Q33786029-02749166-2086-48DB-9E52-7829A67C80B7Q33804205-31F160A2-A919-4132-BB3D-737153C08976Q33813779-DAF77E79-174A-41EA-B07E-07B249B7A668Q33817933-B9E4D0B8-5D0C-4F28-B847-DB0599C4153EQ33818043-F592B585-7F68-4DD1-A8D5-ED2674F6C478Q33835246-99DA9E03-E455-4EE6-9209-029DC19BBBA5Q33841039-FDD0FCB1-AB64-4903-9684-3A27E86FCF02Q33869825-6E8BB93C-4399-4655-B88D-F8CE2AC22461Q34000001-B97EEEF6-DD2A-493E-9456-BEF1BA7C00B0Q34313075-CCA2FED8-A40A-48C1-B88A-342430BF4A8BQ34497332-923309E3-27BD-4171-8B8B-3DF633A50337Q34746476-2269A67F-633D-4B35-891C-0DE51FC00420Q34860648-D41C1850-F2E0-477C-94E0-1F3DF77367DDQ35131227-19E0DE2D-83B3-4CC7-A80D-2FEC23A415C8Q35131229-4CB43447-5448-4E73-9E2A-C944ED0F4090Q35804801-0F86029E-E255-462C-A814-3F0BB192CF8BQ35847178-675B1E7A-3155-4E04-B59D-28B63BC07EA4Q35849770-965D4CD6-74FC-444E-ADC6-F61D6002B49EQ35884548-2FAD3220-0D16-4D8E-BDF2-B19189932788Q35904443-A10B9194-C265-44ED-A5F4-052E990AD4C7Q37394036-8225E78F-2284-4A4B-A355-AF933B5E3A37Q37945219-3DD2D801-2CC4-40CE-A5A5-C58B8A8AE861Q38022486-F7A7F9D2-7D23-47E4-9440-8FB5884AECCEQ38332622-CF5EAC18-2DF1-4153-84BA-084103178CEBQ38820937-F528B0FC-883F-4336-BB35-C19B685BDD45Q39511773-A1622F66-D899-4849-A519-91FEE837CF2EQ39589248-E625BA3E-51EF-4FF6-895F-AAAADD5BCCB3Q39590288-4E1AFEA0-0E0D-4F12-A43E-78CFBF6CE665Q39601191-103990EC-058D-4FB3-A407-2CB09B93BBCAQ40015350-660AD4C7-BCA9-4C0C-9C29-6CD9E84C003EQ40859645-C7AD093E-A801-435C-9CDF-5B7518E2D522
P2860
Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Transient immunomodulation wit ...... ene transfer into mouse liver.
@ast
Transient immunomodulation wit ...... ene transfer into mouse liver.
@en
type
label
Transient immunomodulation wit ...... ene transfer into mouse liver.
@ast
Transient immunomodulation wit ...... ene transfer into mouse liver.
@en
prefLabel
Transient immunomodulation wit ...... ene transfer into mouse liver.
@ast
Transient immunomodulation wit ...... ene transfer into mouse liver.
@en
P2093
P2860
P356
P1476
Transient immunomodulation wit ...... ene transfer into mouse liver.
@en
P2093
C B Wilson
D Hollenbaugh
P2860
P304
P356
10.1073/PNAS.94.9.4686
P407
P577
1997-04-01T00:00:00Z