Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length
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Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stagesCellular Mechanisms of Ciliary Length ControlCurrent topics of functional links between primary cilia and cell cycleCilium assembly and disassemblyThe Cilium: Cellular Antenna and Central Processing UnitCPAP promotes timely cilium disassembly to maintain neural progenitor poolCyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulationCDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.Mechanisms of ciliogenesis suppression in dividing cellsNDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness.Role of primary cilia in non-dividing and post-mitotic cells.Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.The tumor suppressor FBW7 controls ciliary length.EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.Physiological functions of FBW7 in cancer and metabolism.Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.Sending mixed signals: Cilia-dependent signaling during development and disease.M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole
P2860
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P2860
Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@ast
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@en
type
label
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@ast
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@en
prefLabel
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@ast
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@en
P2093
P2860
P356
P1433
P1476
Cell cycle-dependent ubiquityl ...... -FBW7 regulates ciliary length
@en
P2093
Dipak Maskey
E-Ching Ong
Guangpu Li
Leonidas Tsiokas
Sehyun Kim
Seokho Kim
P2860
P304
P356
10.15252/EMBJ.201490831
P407
P577
2015-07-23T00:00:00Z