Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.
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The progress of angiogenic factors in the development of leukemiasA hostel for the hostile: the bone marrow niche in hematologic neoplasmsTargeting hypoxia in the leukemia microenvironmentAKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemiaApoptosis of bone marrow mesenchymal stem cells caused by hypoxia/reoxygenation via multiple pathways.A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic LeukemiaHypoxia promotes chemoresistance in acute lymphoblastic leukemia cell lines by modulating death signaling pathwaysThe Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations.Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models.Tf-PEG-PLL-PLGA nanoparticles enhanced chemosensitivity for hypoxia-responsive tumor cells.The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development.Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact.Integration of hypoxic HIF-α signaling in blood cancers.Deoxycytidine kinase is downregulated under hypoxic conditions and confers resistance against cytarabine in acute myeloid leukaemia.Glycolytic inhibitor 2-deoxy-d-glucose suppresses cell proliferation and enhances methylprednisolone sensitivity in non-Hodgkin lymphoma cells through down-regulation of HIF-1α and c-MYC.Hypoxia-related gene expression profile in childhood acute lymphoblastic leukemia: prognostic implications.PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment.Involvement of c-Jun N-terminal kinase in reversal of multidrug resistance of human leukemia cells in hypoxia by 5-bromotetrandrine.Beclin-1 and hypoxia-inducible factor-1α genes expression: Potential biomarkers in acute leukemia patients.Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer.Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia.Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells.Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACE-induced hypoxia: A biopsy and resection matched study.Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.Knockdown of lncRNA CCAT2 inhibits endometrial cancer cells growth and metastasis via sponging miR-216b.Promoter Methylation Status of Survival-Related Genes in MOLT- 4 Cells Co-Cultured with Bone Marrow Mesenchymal Stem Cells under Hypoxic Conditions.Bone marrow mesenchymal stromal cells affect the cell cycle arrest effect of genotoxic agents on acute lymphocytic leukemia cells via p21 down-regulation.SERUM metabolomics of acute lymphoblastic leukaemia and acute myeloid leukaemia for probing biomarker molecules.Biological Aspects of mTOR in Leukemia
P2860
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P2860
Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@ast
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@en
type
label
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@ast
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@en
prefLabel
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@ast
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@en
P2093
P2860
P50
P356
P1476
Regulation of HIF-1α signaling ...... bone marrow microenvironment.
@en
P2093
Ana Markovic
Daniela Buglio
Deborah Thomas
Elizabeth Shpall
Ismael Samudio
Juliana Maria Benito
Olga Frolova
Richard Lock
Rodrigo Jacamo
P2860
P304
P356
10.4161/CBT.20838
P577
2012-08-01T00:00:00Z