PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma.
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MAPK pathway activation in pilocytic astrocytomaPathological and molecular advances in pediatric low-grade astrocytomaThe therapeutic potential of targeting the PI3K pathway in pediatric brain tumorsPilocytic astrocytoma: a disease with evolving molecular heterogeneityGrb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancerScreening genes crucial for pediatric pilocytic astrocytoma using weighted gene coexpression network analysis combined with methylation data analysis.MR imaging of brain pilocytic astrocytoma: beyond the stereotype of benign astrocytoma.Adult pilocytic astrocytomas: clinical features and molecular analysisBRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.Phenotypic variations in NF1-associated low grade astrocytomas: possible role for increased mTOR activation in a subset.An 80-year experience with optic nerve glioma cases at the Armed Forces Institute of Pathology: evolution from museum to molecular evaluation suggests possibe interventions in the cellular senescence and microglial pathways (an American OphthalmologMolecular and cellular characterization of a zebrafish optic pathway tumor line implicates glia-derived progenitors in tumorigenesis.Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA.Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.The impact of coexisting genetic mutations on murine optic glioma biology.Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic AstrocytomaComparative transcriptomics reveals similarities and differences between astrocytoma grades.Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas.PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper.BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth.MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2.The combination of novel targeted molecular agents and radiation in the treatment of pediatric gliomas.Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas.Integrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle.Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic targetChallenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade GliomaMiR-495 inhibits esophageal squamous cell carcinoma progression by targeting Akt1KIAA0247 suppresses the proliferation, angiogenesis and promote apoptosis of human glioma through inactivation of the AKT and Stat3 signaling pathway.Long-term epilepsy-associated tumors.Malignant transformation in pediatric spinal intramedullary tumors: case-based update.Role of Akt in human malignant glioma: from oncogenesis to tumor aggressiveness.Review of low-grade gliomas in children--evolving molecular era and therapeutic insights.Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome.Diffuse leptomeningeal spread of supratentorial recurrent pilocytic astrocytoma in a child.Contextual signaling in cancer.A comprehensive review of paediatric low-grade diffuse glioma: pathology, molecular genetics and treatment.Pilocytic astrocytoma survival in adults: analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model.
P2860
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P2860
PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@ast
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@en
type
label
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@ast
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@en
prefLabel
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@ast
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@en
P2093
P2860
P1476
PI3K/AKT pathway alterations a ...... sets of pilocytic astrocytoma.
@en
P2093
Amanda Rynearson
Bernd W Scheithauer
Bridget Hoesley
Caterina Giannini
Erika F Rodriguez
Fausto J Rodriguez
Heather Gilmer-Flynn
Jann N Sarkaria
P2860
P2888
P304
P356
10.1007/S00401-010-0784-9
P577
2010-11-28T00:00:00Z