Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2
about
Modern concepts concerning the origin of the heartbeat.Induced Pluripotent Stem Cell-Derived Cardiomyocytes Provide In Vivo Biological Pacemaker FunctionHCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart rates.Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking.Modern perspectives on numerical modeling of cardiac pacemaker cellNumerical models based on a minimal set of sarcolemmal electrogenic proteins and an intracellular Ca(2+) clock generate robust, flexible, and energy-efficient cardiac pacemaking.Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block.Sarcoplasmic reticulum Ca2+ cycling protein phosphorylation in a physiologic Ca2+ milieu unleashes a high-power, rhythmic Ca2+ clock in ventricular myocytes: relevance to arrhythmias and bio-pacemaker design.Gene therapy for restoring heart rhythm.Stem cell-based biological pacemakers from proof of principle to therapy: a review.Gene therapy to restore electrophysiological function in heart failure.Pacing the Heart with Genes: Recent Progress in Biological Pacing.Current state of the art for cardiac arrhythmia gene therapy.Gene Therapy for Cardiac Arrhythmias.Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability.Reprogramming paces the heart.Electrophysiological heterogeneity of pacemaker cells in rabbit intercaval region, including SA node: insights from recording multiple ion currents in each cell.Biological therapies targeting arrhythmias: are cells and genes the answer?Direct Reprograming to Regenerate Myocardium and Repair Its Pacemaker and Conduction System.
P2860
Q27008871-C4549ABB-6118-4B0F-9EEE-7EC2E1E19236Q33698370-9A230859-D11A-4D07-A628-DFD2DCEC1885Q33851176-FB3FCFDC-1939-42BD-87AC-C986294ACA92Q34574809-C17068F5-34A3-4767-92C2-43623D6A7764Q35934714-51DB8EEC-10C9-4398-B9BB-93CCF16507D6Q35961500-8E2FD2CC-841B-4C1D-A461-23B66CAB602EQ37105417-FADCF628-12D7-4819-971C-17075842491CQ37497785-E1BA4D93-5116-498E-9174-CBFC8BCCCF52Q38205308-72F4B847-02A4-442E-A057-D2EBBDC6E6A5Q38212017-2619FF56-D291-4EB2-B32A-7FA4E91B2C20Q38416938-5CF38F2F-CF28-4364-8CB1-742A425E9A4DQ38538855-EFC7C49F-00C1-43E7-AB8A-AFCBBF6102DDQ39392472-7EDC12AB-29F9-4661-919E-872A20250DEAQ39815208-06733094-E1AE-4FD3-A8A0-8037D6D23E99Q41132024-01016089-FE4B-48A2-AF70-05A4F20D7300Q42082753-C7F35332-75C7-49CD-B162-760C65A6AF10Q42515202-BF0AAB0D-C587-4372-844B-B185920D2859Q47286154-A2DD12B4-02FE-493E-8062-4DF8E4CBA7F2Q55419764-F8542931-71F6-4347-A62B-60E2531DCC88
P2860
Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@ast
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@en
type
label
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@ast
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@en
prefLabel
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@ast
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@en
P2093
P2860
P1433
P1476
Ca(2+)-stimulated adenylyl cyc ...... y and in combination with HCN2
@en
P2093
Bruce D Nearing
Gerard J J Boink
Hanno L Tan
Ira S Cohen
Iryna N Shlapakova
Michael R Rosen
Peter Danilo
Richard B Robinson
Richard L Verrier
P2860
P304
P356
10.1161/CIRCULATIONAHA.111.083584
P407
P577
2012-06-29T00:00:00Z