Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization. - Wikidata - wikimedia - TriplyDB

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

http://www.wikidata.org/entity/Q36161382

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The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1)Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer Drosophila lacking microRNA miR-278 are defective in energy homeostasis Stable chromatin binding prevents FoxA acetylation, preserving FoxA chromatin remodeling Nuclear export-independent inhibition of Foxa2 by insulin Mechanisms of oestrogen receptor (ER) gene regulation in breast cancer Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease MicroRNAs: a new ray of hope for diabetes mellitus The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2 FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo Identification of DNA-dependent protein kinase as a cofactor for the forkhead transcription factor FoxA2 Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M TXNIP regulates peripheral glucose metabolism in humans.Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells.MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms.Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver.Ketone bodies as signaling metabolites.FoxOs function synergistically to promote glucose production.Hepatic nuclear factor 3 and nuclear factor 1 regulate 5-aminolevulinate synthase gene expression and are involved in insulin repression.Molecular mechanisms of insulin resistance.Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.FOXA1 as a therapeutic target for breast cancer.Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes Molecular mechanisms of insulin resistance in type 2 diabetes mellitus Post-translational modification of pregnane x receptor.SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling β-hydroxybutyrate: much more than a metabolite The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression.Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.Calorie hoarding and thrifting: Foxa3 finds a way.Pregnane X Receptor Represses HNF4α Gene to Induce Insulin-Like Growth Factor-Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells.Insulin's expanding control of forkheads.Therapeutic potential of mesenchymal stem cells overexpressing human forkhead box A2 gene in the regeneration of damaged liver tissues

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Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

http://www.wikidata.org/entity/Q36161382

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Insulin regulates the activity ...... uclear/cytosolic localization.

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Insulin regulates the activity ...... uclear/cytosolic localization.

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Insulin regulates the activity ...... uclear/cytosolic localization.

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Insulin regulates the activity ...... uclear/cytosolic localization.

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Insulin regulates the activity ...... uclear/cytosolic localization.

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Insulin regulates the activity ...... uclear/cytosolic localization.

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PNAS.1931483100

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Proceedings of the National Academy of Sciences of the United States of America

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Insulin regulates the activity ...... nuclear/cytosolic localization

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Edlira Luca

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Markus Stoffel

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues

Targeted disruption of the gene encoding hepatocyte nuclear factor 3gamma results in reduced transcription of hepatocyte-specific genes.

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

A C. elegans mutant that lives twice as long as wild type

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11624-11629

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20

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100

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Christian Wolfrum

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2003-09-19T00:00:00Z

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9087748

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14500912

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phosphorylation

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208808

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