Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1
about
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasmThe final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'-->3' exonucleasesNob1p is required for cleavage of the 3' end of 18S rRNADiazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunitThe 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage siteProcessing of preribosomal RNA in Saccharomyces cerevisiaeRok1p is a putative RNA helicase required for rRNA processingRNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1.Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p.Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic proteinRrp5p, a trans-acting factor in yeast ribosome biogenesis, is an RNA-binding protein with a pronounced preference for U-rich sequences.Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunitsNuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.Dbp3p, a putative RNA helicase in Saccharomyces cerevisiae, is required for efficient pre-rRNA processing predominantly at site A3.Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectivelyRole of Mex67-Mtr2 in the nuclear export of 40S pre-ribosomes.A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.NDT80, a meiosis-specific gene required for exit from pachytene in Saccharomyces cerevisiae.The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity.The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology.Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43pTemperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae.Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast.Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiaeSaccharomyces cerevisiae Nip7p is required for efficient 60S ribosome subunit biogenesis.Processing of the precursors to small nucleolar RNAs and rRNAs requires common components.A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substratesYeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structureProtein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiaeTOR regulates the subcellular distribution of DIM2, a KH domain protein required for cotranscriptional ribosome assembly and pre-40S ribosome export.Dominant mutations in the late 40S biogenesis factor Ltv1 affect cytoplasmic maturation of the small ribosomal subunit in Saccharomyces cerevisiaeLithium toxicity in yeast is due to the inhibition of RNA processing enzymes.Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis.A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly.The yeast ubiquitin protease, Ubp3p, promotes protein stabilityAccelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme.Analysis of two domains with novel RNA-processing activities throws light on the complex evolution of ribosomal RNA biogenesis.Novel features of the XRN-family in Arabidopsis: evidence that AtXRN4, one of several orthologs of nuclear Xrn2p/Rat1p, functions in the cytoplasm.
P2860
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P2860
Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@ast
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@en
type
label
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@ast
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@en
prefLabel
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@ast
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@en
P2093
P2860
P1476
Fragments of the internal tran ...... ing 5'----3' exoribonuclease 1
@en
P2093
P2860
P304
P356
10.1128/JB.173.21.7024-7028.1991
P407
P577
1991-11-01T00:00:00Z