Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism
about
Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complexPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexAnimal models to study the mutational landscape for oral cavity and oropharyngeal cancersViral and Cellular Determinants of the Hepatitis C Virus Envelope-Heparan Sulfate InteractionTelomere maintenance in laser capture microdissection-purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivo.Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis.Alternative lengthening of telomeres in mammalian cells.Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres.Cox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditionsOpportunities and challenges facing biomarker development for personalized head and neck cancer treatment.Cancer of the esophagus and gastric cardia: recent advances.Cortactin expression predicts poor survival in laryngeal carcinomaTopical Application of Green Tea Polyphenol (-)-Epigallocatechin-3-gallate (EGCG) for Prevention of Recurrent Oral Neoplastic LesionsInduction of intestinalization in human esophageal keratinocytes is a multistep processTargeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.Reviewing once more the c-myc and Ras collaboration: converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology.Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation.Genomic sequencing and precision medicine in head and neck cancers.miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes.Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.An alternative lifestyle for immortalized oral keratinocytes.p53 differentially inhibits cell growth depending on the mechanism of telomere maintenanceCellular senescence requires CDK5 repression of Rac1 activity.Altered expression of cell-cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors.Correlation of dyskerin expression with active proliferation independent of telomerase.Biomarkers in Tumorigenesis Using Cancer Cell Lines: A Systematic ReviewEGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.Telomerase Activity and Telomere Length in Primary and Metastatic Tumors from Pediatric Bone Cancer Patients
P2860
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P2860
Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@ast
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@en
type
label
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@ast
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@en
prefLabel
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@ast
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@en
P2093
P2860
P356
P1476
Cyclin D1 overexpression and p ...... lomerase-independent mechanism
@en
P2093
P2860
P304
P356
10.1172/JCI200111909
P407
P577
2001-09-01T00:00:00Z