Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. - Wikidata - wikimedia - TriplyDB

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

http://www.wikidata.org/entity/Q36174537

about

Genome-wide association study of antibody response to smallpox vaccine Responses to Microbial Challenges by SLAMF Receptors Molecular mechanisms of T cell co-stimulation and co-inhibition The Novel PKCθ from Benchtop to Clinic Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity Fine specificity and molecular competition in SLAM family receptor signalling The adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling.SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice.Fyn kinase is required for optimal humoral responses.Emerging concepts on T follicular helper cell dynamics in HIV infection CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development.Chronic activation of the kinase IKKβ impairs T cell function and survival.CD4 T follicular helper cell dynamics during SIV infection SAP is required for the development of innate phenotype in H2-M3--restricted Cd8(+) T cells.Role of diacylglycerol kinases in T cell development and function.Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination.Role of anti-inflammatory cytokines IL-4 and IL-13 in systemic sclerosis.T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders.Insights into the development and regulation of T follicular helper cells.Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity.Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology

P2860

Q24612100-780D12C5-1C99-47C6-BC63-B1D9BC714FB0 Q26772707-67D52784-E38B-4355-9E92-5C63795ACB8D Q26864888-E1DDA2F9-F120-42E7-A698-92D248C300A7 Q27024068-AC229895-33B5-493C-8FDC-09E02451AA0E Q28066088-8B4DA632-29C7-4129-AFFC-D3F4A56D6512 Q28118752-640E02AF-DF4C-414F-96D3-E2C1E05B446E Q30010025-74F7541F-AB27-4F91-8D1A-EE3EC73A6E82 Q30010214-4A03C668-1CB8-4384-91AA-0DDB2F3F6CC7 Q34663968-090E60F7-E2D1-463C-887F-CD7B600677F9 Q34673602-2F200B58-8510-45DC-A9A0-C0A789634F5E Q34687653-0FBB5786-49FD-4ABF-948E-E47C3368BEE1 Q36029118-8B29C6C9-E07E-4186-BDEF-2ACC8AFDF2F7 Q36039901-E33F8FAB-D2B3-47AA-9311-310D358ADCBB Q36074906-BFACFCA7-F9D6-4A2F-B706-F5674F395DCA Q36106570-97387727-96A6-4655-8B4F-D1FB6A99160B Q36190736-F500DD38-2CAC-4917-AFF3-BBE2A9C23576 Q36374279-ACDC0FF4-1A69-428C-AE03-7DC3281FB35E Q36946379-6BA0089F-09B1-48E8-AAF5-AB0EDC596B95 Q38112537-B4C65A5D-D93B-4BB7-89BA-394A3598AD7D Q38366114-753DE857-6EC8-4FE8-B8A8-421EAB3C919F Q38771318-C3803939-E5D1-4644-8469-57770F23D770 Q38875184-219F65F6-1C16-47E4-A41A-A4CD44BAFD38 Q41772229-4086E9D2-7AAF-425C-B25F-EEC690CFAF6D Q58777530-79AD905D-ADEC-4F4E-B818-F1299B851F4B

P2860

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

http://www.wikidata.org/entity/Q36174537

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@ast

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@en

type

label

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@ast

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@en

prefLabel

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@ast

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@en

P1433

Q36174537-27F982EB-89D9-4FFB-8910-9E69BEB34F52

P1476

Q36174537-D42AA458-8CCD-40F7-9D06-EC1B145156F3

P2093

Q36174537-4537EF89-105D-446C-BC6B-03F0627A4786

Q36174537-78A2C291-5B78-4A88-A9FC-821DFBF3E17D

Q36174537-7D335CE3-70C1-4184-9AE7-1A1D6D88C3EB

Q36174537-8C799B46-4C5F-4156-BFE1-BCEC9CF0B593

Q36174537-970EA2EA-776E-4ECF-9D78-6DC7801DA4D4

Q36174537-AD7412F1-B9A6-4220-A5A2-F167E68D2156

Q36174537-B39C9329-9E59-467D-9258-3196D7008D01

Q36174537-E7C1C7E0-DEA8-4D82-BB92-078BBED3E256

Q36174537-ED748769-5127-454F-A4C9-C0A81B2688CD

P2860

Q36174537-01B5DC06-6B33-4B87-8BFC-1D44621CDAE6

Q36174537-0A64F717-F7AB-4866-9093-B78421D21D36

Q36174537-147E8B54-0ACC-458C-870A-03743B74A659

Q36174537-1848DAEC-84F4-4E3E-92D5-47CB1BCE70B0

Q36174537-189EB202-3A44-47DE-9D68-783AF855BA69

Q36174537-1A9F60FF-F140-4814-89E1-73BC5BFFAE1A

Q36174537-33A80825-AC33-472C-B122-5D4BB8220177

Q36174537-35422009-E604-46B9-A2E1-93132E00E621

Q36174537-362EA304-5B3D-47FA-90F6-3F82F9818F93

Q36174537-3775C5AB-D60C-497D-BD12-1F9AD61343A5

P304

Q36174537-94F49D80-6A21-469C-83A1-2DD323871A6B

P31

Q36174537-8280BEB4-464A-4AE5-9E78-13542118270F

P356

Q36174537-5197E1A4-ECEA-499D-BB19-4729F8EF7981

P407

Q36174537-80E541DE-02E5-441E-8B88-6D2F6E911791

P433

Q36174537-8BB8636B-3BB4-4650-AFCE-F330731DAC07

P478

Q36174537-9B926C3C-C845-4504-8042-DF2EB01F5CB2

P577

Q36174537-7F50FDAB-A5E1-4B37-94F3-9E6D25137B48

P5875

Q36174537-9E6CAF6F-EFB1-4F75-9C15-F1A8C2340EA6

P698

Q36174537-1AF5ED75-8FE0-4D21-A00B-15819F727FD4

P932

Q36174537-5B09A300-0FA0-4C48-95BB-705D5A8C8113

P356

JIMMUNOL.0902182

P1433

Journal of Immunology

P1476

Biochemical and genetic eviden ...... ntributing to IL-4 regulation.

@en

P2093

Baoxia Dong

http://www.w3.org/2001/XMLSchema#string

Jennifer L Cannons

http://www.w3.org/2001/XMLSchema#string

Jinyi Zhang

http://www.w3.org/2001/XMLSchema#string

Julie Z Wu

http://www.w3.org/2001/XMLSchema#string

Julio Gomez-Rodriguez

http://www.w3.org/2001/XMLSchema#string

Katherine A Siminovitch

http://www.w3.org/2001/XMLSchema#string

Pamela L Schwartzberg

http://www.w3.org/2001/XMLSchema#string

Stephen Shaw

http://www.w3.org/2001/XMLSchema#string

Yin Liu

http://www.w3.org/2001/XMLSchema#string

P2860

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation

SAP couples Fyn to SLAM immune receptors

Regulation of Fyn through translocation of activated Lck into lipid rafts

Disease-causing SAP mutants are defective in ligand binding and protein folding

The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation

Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL

Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

T follicular helper cells differentiate from Th2 cells in response to helminth antigens

P304

2819-2827

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.0902182

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

185

http://www.w3.org/2001/XMLSchema#string

P577

2010-07-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45406591

http://www.w3.org/2001/XMLSchema#string

P698

20668219

http://www.w3.org/2001/XMLSchema#string

P932

3422635

http://www.w3.org/2001/XMLSchema#string