COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites.
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Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimerSafety issues of current analgesics: an updateSynergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysisEffects of indomethacin-loaded nanocapsules in experimental models of inflammation in ratsRelative efficacy of topical non-steroidal anti-inflammatory drugs and topical capsaicin in osteoarthritis: protocol for an individual patient data meta-analysis.Pharmacokinetic-pharmacodynamic modeling of diclofenac in normal and Freund's complete adjuvant-induced arthritic rats.The nociceptive and anti-nociceptive effects of bee venom injection and therapy: a double-edged swordMethylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds.Interactions of estradiol and NSAIDS on carrageenan-induced hyperalgesia.Estradiol-induced antinociceptive responses on formalin-induced nociception are independent of COX and HPA activation.Anti-inflammatory and antinociceptive activity of ouabain in mice.COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation.Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids.Semi-mechanistic modeling of the interaction between the central and peripheral effects in the antinociceptive response to lumiracoxib in rats.Analgesic and Toxicity Studies of Aminoacetylenic Isoindoline-1,3-dione Derivatives.Rocuronium-induced withdrawal movement: influence of ketorolac or a combination of lidocaine and ketorolac pretreatment.Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis.Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair.Arthritis and pain. Current approaches in the treatment of arthritic painHydrogen sulfide protects against amyloid beta-peptide induced neuronal injury via attenuating inflammatory responses in a rat model.COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice.Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response.Constitutive cyclooxygenase-2 is involved in central nociceptive processes in humans.The use of nonsteroidal anti-inflammatory drugs for exercise-induced muscle damage: implications for skeletal muscle development.Treatment guidelines: implications for community-based headache treatment.Muscles and their role in episodic tension-type headache: implications for treatment.Supra-Additive Interaction of Docosahexaenoic Acid and Naproxen and Gastric Safety on the Formalin Test in Rats.Natural remedies for non-steroidal anti-inflammatory drug-induced toxicity.Investigational drugs targeting the prostaglandin E2 signaling pathway for the treatment of inflammatory pain.Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.Efficacy of celecoxib for acute pain management following total hip arthroplasty in elderly patients: A prospective, randomized, placebo-control trialHC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivityAnalgesic Effects of Danggui-Shaoyao-San on Various "Phenotypes" of Nociception and Inflammation in a Formalin Pain Model.Microglial Janus kinase/signal transduction and activator of transcription 3 pathway activity directly impacts astrocyte and spinal neuron characteristics.Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of 2-(4-isobutylphenyl)propionic acid.Equivalent intraperitoneal doses of ibuprofen supplemented in drinking water or in diet: a behavioral and biochemical assay using antinociceptive and thromboxane inhibitory dose-response curves in mice.Central effects of acetylsalicylic acid on trigeminal-nociceptive stimuliSore throat: effective communication delivers improved diagnosis, enhanced self-care and more rational use of antibiotics.NCX 2057, a novel NO-releasing derivative of ferulic acid, suppresses inflammatory and nociceptive responses in in vitro and in vivo models.Epidural insertion height for ureteric reimplant surgery; does location matter?
P2860
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P2860
COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
COX-dependent mechanisms invol ...... central and peripheral sites.
@ast
COX-dependent mechanisms invol ...... central and peripheral sites.
@en
type
label
COX-dependent mechanisms invol ...... central and peripheral sites.
@ast
COX-dependent mechanisms invol ...... central and peripheral sites.
@en
prefLabel
COX-dependent mechanisms invol ...... central and peripheral sites.
@ast
COX-dependent mechanisms invol ...... central and peripheral sites.
@en
P1476
COX-dependent mechanisms invol ...... central and peripheral sites.
@en
P2093
Gerd Geisslinger
Maria Burian
P304
P356
10.1016/J.PHARMTHERA.2005.02.004
P577
2005-04-19T00:00:00Z