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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

http://www.wikidata.org/entity/Q36184793

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Immunomodulatory properties of HLA-G in infectious diseases Cutaneous squamous cell cancer (cSCC) risk and the human leukocyte antigen (HLA) system.Case-control study of HLA-G promoter methylation status, HPV infection and cervical neoplasia in Curitiba, Brazil: a pilot analysis.Significance of tumour cell HLA-G5/-G6 isoform expression in discrimination for adenocarcinoma from squamous cell carcinoma in lung cancer patients.Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma.Extravillous trophoblast and decidual natural killer cells: a remodelling partnership.Human leukocyte antigen (HLA)-G gene polymorphism in patients with non-small cell lung cancer Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment.HLA-G expression in cancers: roles in immune evasion, metastasis and target for therapy Human leukocyte antigen-G is frequently expressed in glioblastoma and may be induced in vitro by combined 5-aza-2'-deoxycytidine and interferon-γ treatments: results from a multicentric study.Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2.HLA-G dimers in the prolongation of kidney allograft survival.HLA-G expression on blasts and tolerogenic cells in patients affected by acute myeloid leukemia.Immunotherapy biomarkers 2016: overcoming the barriers.Nanoparticles targeting HLA-G for gene therapy in cancer.HLA-G regulators in cancer medicine: an outline of key requirements.The immunosuppressive molecule HLA-G and its clinical implications.Shaping of NK cell responses by the tumor microenvironment New insights into HLA-G mediated tolerance.Evaluation of bone marrow as a metastatic site of human neuroblastoma.Importance of the plasma soluble HLA-G levels for prognostic stratification with traditional prognosticators in colorectal cancer.Identification of 14-3-3β gene as a novel miR-152 target using a proteome-based approach.HLA-G expression is associated with metastasis and poor survival in the Balb/c nu/nu murine tumor model with ovarian cancer.Human Leukocyte antigen-G (HLA-G) and gastrointestinal malignancy.Inhibition of human gamma delta [corrected] T-cell antitumoral activity through HLA-G: implications for immunotherapy of cancer.Immunogenetics of prostate cancer and benign hyperplasia--the potential use of an HLA-G variant as a tag SNP for prostate cancer risk.Co-expression of ILT4/HLA-G in human non-small cell lung cancer correlates with poor prognosis and ILT4-HLA-G interaction activates ERK signaling.The discovery of HLA-G-bearing extracellular vesicles: new perspectives in HLA-G biology.HLA-mediated tumor escape mechanisms that may impair immunotherapy clinical outcomes via T-cell activation Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".MHC class I expression in HPV positive and negative tonsillar squamous cell carcinoma in correlation to clinical outcome.Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features.Association between sHLA-G and HLA-G 14-bp deletion/insertion polymorphism in Crohn's disease.Genetic diversity of the HLA-G coding region in Amerindian populations from the Brazilian Amazon: a possible role of natural selection.Human leukocyte antigen-G expression and polymorphisms promote cancer development and guide cancer diagnosis/treatment.The genetic diversity within the 1.4 kb HLA-G 5' upstream regulatory region moderately impacts on cellular microenvironment responses.Non Melanoma Skin Cancer Pathogenesis Overview.Association of serum soluble human leukocyte antigen-G levels with chronic hepatitis B virus infection.Activities of stromal and immune cells in HPV-related cancers.

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

http://www.wikidata.org/entity/Q36184793

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2010 nî lūn-bûn

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Cellular and Molecular Life Sciences

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Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

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Barbara Seliger

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Hans Grosse-Wilde

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Laurence Amiot

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Soldano Ferrone

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P2860

HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance

Disulfide bond-mediated dimerization of HLA-G on the cell surface.

MicroRNAs: genomics, biogenesis, mechanism, and function

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

HLA-G in skin cancer: a wolf in sheep's clothing?

Beyond the increasing complexity of the immunomodulatory HLA-G molecule

HLA-G-treated tolerogenic dendritic cells induce tolerogenic potential by increasing expression of B7-1 (CD80) molecules

cDNA cloning, protein structure modeling of rhesus monkey (Macaca mulatta) prothrombin.

RREB-1 is a transcriptional repressor of HLA-G.

How do NK cells sense the expression of HLA-G class Ib molecules?

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