about
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cellsInhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growthDiagnosis and management of MELAS.Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells.Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetatePhosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons.Dichloroacetate Decreases Cell Health and Activates Oxidative Stress Defense Pathways in Rat Alveolar Type II PneumocytesTargeting of two aspects of metabolism in breast cancer treatment.Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.Cardiac-Specific Deletion of the Pdha1 Gene Sensitizes Heart to Toxicological Actions of Ischemic Stress.Regulation of muscle pyruvate dehydrogenase complex in insulin resistance: effects of exercise and dichloroacetateDrugs and insulin resistance: clinical methods of evaluation and new pharmacological approaches to metabolism.The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 PathwayIncreasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study.The role of FOXO and PPAR transcription factors in diet-mediated inhibition of PDC activation and carbohydrate oxidation during exercise in humans and the role of pharmacological activation of PDC in overriding these changesLactate interferes with ATP release from red blood cells.Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status.Renal Energy Metabolism Following Acute Dichloroacetate and 2,4-Dinitrophenol Administration: Assessing the Cumulative Action with Hyperpolarized [1-C]Pyruvate MRI
P2860
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P2860
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Dichloroacetate.
@ast
Dichloroacetate.
@en
type
label
Dichloroacetate.
@ast
Dichloroacetate.
@en
prefLabel
Dichloroacetate.
@ast
Dichloroacetate.
@en
P356
P1433
P1476
Dichloroacetate.
@en
P2093
Stacpoole PW
P304
P356
10.2337/DIACARE.15.6.785
P407
P577
1992-06-01T00:00:00Z