Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells. - Wikidata - wikimedia - TriplyDB

Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells.

Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells.

http://www.wikidata.org/entity/Q36202900

about

Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease The pericyte: a forgotten cell type with important implications for Alzheimer's disease?Immunohistochemical study of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 in the hippocampal vasculature: pathological synergy of Alzheimer's disease and diabetes mellitus LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.Phagocytic clearance in neurodegeneration.Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.Central nervous system pericytes in health and disease.Biomarkers of inflammation and amyloid-beta phagocytosis in patients at risk of Alzheimer disease.Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy.Apolipoprotein E and LRP1 Increase Early in Parkinson's Disease Pathogenesis.Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1.Capillary dysfunction: its detection and causative role in dementias and stroke Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier.High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity.Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma.Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease.Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.Transport characteristics of a novel peptide platform for CNS therapeutics.Pericyte loss influences Alzheimer-like neurodegeneration in mice.Delivery of a peptide-drug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma.Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease Brain microvascular pericytes in health and disease.Tissue transglutaminase: a novel therapeutic target in cerebral amyloid angiopathy.The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD.Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.The potential mechanisms of Aβ-receptor for advanced glycation end-products interaction disrupting tight junctions of the blood-brain barrier in Alzheimer's disease.The role of pericytes in neurovascular unit remodeling in brain disorders.Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood-brain barrier.The blood-brain barrier in Alzheimer's disease.Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide Haptoglobin modulates beta-amyloid uptake by U-87 MG astrocyte cell line.Involvement of matrix metalloproteinase-9 in amyloid-β 1-42-induced shedding of the pericyte proteoglycan NG2.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease.Multifunctional role of astrocytes as gatekeepers of neuronal energy supply Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity.

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P2860

Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells.

http://www.wikidata.org/entity/Q36202900

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Staging of brain pathology related to sporadic Parkinson's disease

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.

beta-Amyloid efflux mediated by p-glycoprotein.

Cerebral amyloid angiopathy: accumulation of A beta in interstitial fluid drainage pathways in Alzheimer's disease.

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

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