about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerTowards a quantitative understanding of mitotic spindle assembly and mechanicsKinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cellsKIFC1: a promising chemotherapy target for cancer treatment?Drugging the addict: non-oncogene addiction as a target for cancer therapyCentrosome Aberration Frequency and Disease Association in B-Acute Lymphoblastic Leukemia.Causes and consequences of centrosome abnormalities in cancer.Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage.Centrosome amplification and the development of cancer.Targeting karyotypic complexity and chromosomal instability of cancer cells.Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer.Intranuclear membranes and the formation of the first meiotic spindle in Xenos peckii (Acroschismus wheeleri) oocytesInterconversion of metaphase and interphase microtubule arrays, as studied by the injection of centrosomes and nuclei into Xenopus eggsExperimental separation of pronuclei in fertilized sea urchin eggs: chromosomes do not organize a spindle in the absence of centrosomes.Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes.A nucleus-basal body connector in Chlamydomonas reinhardtii that may function in basal body localization or segregationEpidermal development, growth control, and homeostasis in the face of centrosome amplificationAnalysis of the cellular centrosome in fine-needle aspirations of the breast.Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes.Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitosesCentrosome amplification can initiate tumorigenesis in flies.Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variantsMultiple centrosomes: together they stand, divided they fall.Multi-layered cancer chromosomal instability phenotype.Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.The life cycle of centriolesMetaphase Spindle Assembly.Mitosis as an anti-cancer target.Centrosome clustering and chromosomal (in)stability: a matter of life and death.Centrosomes and cilia in human disease.The centrosome as potential target for cancer therapy and prevention.The importance of a single primary cilium.Mitotic spindle multipolarity without centrosome amplification.The centrosome duplication cycle in health and disease.The Janus soul of centrosomes: a paradoxical role in disease?Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals.Dividing with Extra Centrosomes: A Double Edged Sword for Cancer Cells.Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.
P2860
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P2860
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Mitosis in a cell with multiple centrioles
@ast
Mitosis in a cell with multiple centrioles
@en
type
label
Mitosis in a cell with multiple centrioles
@ast
Mitosis in a cell with multiple centrioles
@en
prefLabel
Mitosis in a cell with multiple centrioles
@ast
Mitosis in a cell with multiple centrioles
@en
P2093
P2860
P356
P1476
Mitosis in a cell with multiple centrioles
@en
P2093
P2860
P304
P356
10.1083/JCB.94.3.549
P407
P577
1982-09-01T00:00:00Z