Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
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Autophagy in the physiology and pathology of the central nervous systemGenetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type CAccumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neuronsEnhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisSignals from the lysosome: a control centre for cellular clearance and energy metabolism.Direct conversion of fibroblasts into functional astrocytes by defined transcription factorsTranscriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis.Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.Methylene blue protects astrocytes against glucose oxygen deprivation by improving cellular respiration.Time-Dependent Changes in Apoptosis Upon Autophagy Inhibition in Astrocytes Exposed to Oxygen and Glucose Deprivation.Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammationAstrocytes and lysosomal storage diseases.Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretionIncreased Number of Plasma B Cells Producing Autoantibodies Against Aβ42 Protofibrils in Alzheimer's Disease.New targets for old diseases: lessons from mucolipidosis type II.Autophagy and amino acid metabolism in the brain: implications for epilepsy.α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading.Combination Therapies for Lysosomal Storage Diseases: A Complex Answer to a Simple Problem.Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization.The Role of Astrocyte Dysfunction in Parkinson's Disease Pathogenesis.Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments.Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes.Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons.Astrocytosis in infantile neuronal ceroid lipofuscinosis: friend or foe?Cytotoxic Effects of Environmental Toxins on Human Glial Cells.Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification.Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis
P2860
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P2860
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@ast
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@en
type
label
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@ast
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@en
prefLabel
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@ast
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@en
P2860
P356
P1476
Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.
@en
P2093
Chiara Di Malta
John D Fryer
P2860
P304
P356
10.1073/PNAS.1209577109
P407
P577
2012-07-23T00:00:00Z