Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis - Wikidata - wikimedia - TriplyDB

Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis

Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis

http://www.wikidata.org/entity/Q36212936

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Functions of heat shock proteins in pathways of the innate and adaptive immune system High molecular weight stress proteins: Identification, cloning and utilisation in cancer immunotherapy Active suppression induced by repetitive self-epitopes protects against EAE development Role of endoplasmic reticulum stress in rheumatoid arthritis pathogenesis.Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy Heat shock proteins (HSPs) in the homeostasis of regulatory T cells (Tregs)Tolerization against atherosclerosis using heat shock protein 60 Chloroquine treatment enhances regulatory T cells and reduces the severity of experimental autoimmune encephalomyelitis Goals in Nutrition Science 2015-2020 T cell recognition of naturally presented epitopes of self-heat shock protein 70.Heat Shock Proteins: Intestinal Gatekeepers that Are Influenced by Dietary Components and the Gut Microbiota In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4+CD25- T Cells Using an Hsp70 Peptide.Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity.Immune responses to Mycobacterial heat shock protein 70 accompany self-reactivity to human BiP in rheumatoid arthritis Generation of the First TCR Transgenic Mouse with CD4(+) T Cells Recognizing an Anti-inflammatory Regulatory T Cell-Inducing Hsp70 Peptide Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis Heat shock proteins and regulatory T cells Heat-shock proteins in autoimmunity.Mycobacterial and mouse HSP70 have immuno-modulatory effects on dendritic cells.Stem Cell-Derived Regulatory T Cells for Therapeutic Use in Arthritis.Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity.Stress proteins are used by the immune system for cognate interactions with anti-inflammatory regulatory T cells.Heat shock proteins can be targets of regulatory T cells for therapeutic intervention in rheumatoid arthritis.Heat shock protein 70 - the next chaperone to target in the treatment of human acute myelogenous leukemia?The virus-induced HSPs regulate the apoptosis of operatus APCs that result in autoimmunity, not in homeostasis.The therapeutic potential of regulatory T cells for the treatment of autoimmune disease.T- and B-cell subsets in periodontitis.T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity.Immunization of BALB/c mice with pigeon IgY induces the production of anti-IgG autoantibodies.Heat shock proteins and their immunomodulatory role in inflammatory arthritis.Tumor-derived inducible heat-shock protein 70 (HSP70) is an essential component of anti-tumor immunity.Engineered regulatory T cells coexpressing MHC class II:peptide complexes are efficient inhibitors of autoimmune T cell function and prevent the development of autoimmune arthritis.Amelioration of EAE by a cryptic epitope of myelin oligodendrocyte glycoprotein.Targeting of tolerogenic dendritic cells towards heat shock proteins: a novel therapeutic strategy for autoimmune diseases?Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition.Idiopathic pulmonary fibrosis pathogenesis and novel approaches to immunomodulation: we must not be tyrannized by the PANTHER data.T Cell-Mediated Chronic Inflammatory Diseases Are Candidates for Therapeutic Tolerance Induction with Heat Shock Proteins.The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins.The Enigma of Heat Shock Proteins in Immune Tolerance.BiP, From Putting Out Fires to Fanning the Flames in Rheumatoid Arthritis.

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Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis

http://www.wikidata.org/entity/Q36212936

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PNAS.1206803109

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Proceedings of the National Academy of Sciences of the United States of America

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Regulatory T cells that recogn ...... essors of autoimmune arthritis

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Aad Hoek

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Cécile A C M van Els

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Hugo D Meiring

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Ineke den Braber

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Josée P Wagenaar-Hilbers

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Lotte Wieten

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Mahavir Singh

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Peter J van Kooten

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Stephen M Anderton

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Willem van Eden

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P2860

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

The stressed synovium

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

How regulatory T cells work

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

Mechanisms of foxp3+ T regulatory cell-mediated suppression

Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node.

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35

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109

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Ruurd van der Zee

Martijn J van Herwijnen

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2012-08-13T00:00:00Z

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230666807

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