Generation and characterization of a target-selectively activated antibody against epidermal growth factor receptor with enhanced anti-tumor potency.
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Stability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the VL framework using a structure-guided approachPreclinical studies of a Pro-antibody-drug conjugate designed to selectively target EGFR-overexpressing tumors with improved therapeutic efficacy.Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains.
P2860
Generation and characterization of a target-selectively activated antibody against epidermal growth factor receptor with enhanced anti-tumor potency.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Generation and characterizatio ...... h enhanced anti-tumor potency.
@ast
Generation and characterizatio ...... h enhanced anti-tumor potency.
@en
type
label
Generation and characterizatio ...... h enhanced anti-tumor potency.
@ast
Generation and characterizatio ...... h enhanced anti-tumor potency.
@en
prefLabel
Generation and characterizatio ...... h enhanced anti-tumor potency.
@ast
Generation and characterizatio ...... h enhanced anti-tumor potency.
@en
P2093
P2860
P1476
Generation and characterizatio ...... h enhanced anti-tumor potency.
@en
P2093
Huaizu Guo
Qingcheng Guo
Xiaoyun Peng
P2860
P304
P356
10.1080/19420862.2015.1008352
P577
2015-01-01T00:00:00Z