The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.
about
Isolation, cloning, and sequence analysis of the integrin subunit alpha10, a beta1-associated collagen binding integrin expressed on chondrocytesPlatelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptorStructure and function of the platelet integrin alphaIIbbeta3Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteinsIntegrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8Microfluidics and coagulation biologySelection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3Crystal structure of the I domain from integrin alpha2beta1Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagenMammary epithelial cell-cycle progression via the alpha(2)beta(1) integrin: unique and synergistic roles of the alpha(2) cytoplasmic domainHigh-speed platelet adhesion under conditions of rapid flow.Platelet adhesion to collagen via the alpha 2 beta 1 integrin under arterial flow conditions causes rapid tyrosine phosphorylation of pp125FAK.Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.Cyclic AMP does not inhibit collagen-induced platelet signal transductionEvidence that adhesion of electrically permeabilized platelets to collagen is mediated by guanine nucleotide regulatory proteinsCytosolic calcium as a second messenger for collagen-induced platelet responses.Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing.Functional roles of membrane glycoprotein CD36.Matrix metalloproteinases in repair.Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice.The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2)Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cellsThe integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms.Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory responseArginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding.The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages.α2β1 integrin, GPVI receptor, and common FcRγ chain on mouse platelets mediate distinct responses to collagen in models of thrombosisMolecular cloning of the rat integrin alpha 1-subunit: a receptor for laminin and collagenTranscriptome analysis of human peripheral blood mononuclear cells exposed to Lassa virus and to the attenuated Mopeia/Lassa reassortant 29 (ML29), a vaccine candidateOsteocyte and osteoblast apoptosis and excessive bone deposition accompany failure of collagenase cleavage of collagenThe alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis.Collagen receptor control of epithelial morphogenesis and cell cycle progression.Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast.Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptorExpression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases.Extracellular matrix components induce endocrine differentiation in vitro in NCI-H716 cells.Dynamic expression of alpha 1 beta 1 and alpha 2 beta 1 integrin receptors by human vascular smooth muscle cells. Alpha 2 beta 1 integrin is required for chemotaxis across type I collagen-coated membranesThe regulation of integrin function by divalent cations.Integrin expression and ability to adhere to extracellular matrix proteins and endothelial cells in human lung cancer lines.
P2860
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P2860
The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@ast
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@en
type
label
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@ast
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@en
prefLabel
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@ast
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@en
P2093
P2860
P356
P1476
The membrane glycoprotein Ia-I ...... sion of platelets to collagen.
@en
P2093
E A Wayner
S A Santoro
S M Rajpara
W D Staatz
W G Carter
P2860
P304
P356
10.1083/JCB.108.5.1917
P407
P577
1989-05-01T00:00:00Z