Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo.
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Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilinRin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22Immunoelectron microscope analysis of epidermal growth factor receptor (EGFR) in isolated Mytilus galloprovincialis (Lam.) digestive gland cells: evidence for ligand-induced changes in EGFR intracellular distribution.Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factorInternalization of vasopressin analogs in kidney and smooth muscle cells: evidence for receptor-mediated endocytosis in cells with V2 or V1 receptorsDown-regulation of cell surface receptors is modulated by polar residues within the transmembrane domain.A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation.FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation.Role of lipid rafts in liver health and diseaseLigand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization.Epidermal growth factor-induced vacuolar (H+)-atpase assembly: a role in signaling via mTORC1 activation.Selective degradation of insulin within rat liver endosomes.Consumption of EGF by A431 cells: evidence for receptor recyclingAn endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells.Targeted polymers for gene delivery.Adenovirus E3 protein causes constitutively internalized epidermal growth factor receptors to accumulate in a prelysosomal compartment, resulting in enhanced degradationMembrane biochemistry and chemical hepatocarcinogenesis.Radical decisions in cancer: redox control of cell growth and death.Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway.Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1.Extracellular matrix modulates epidermal growth factor receptor activation in rat glomerular epithelial cells.Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma.Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo.A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo.Identification of a 190-kDa vascular endothelial growth factor 165 cell surface binding protein on a human glioma cell line.Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes.Uptake and metabolic fate of [HisA8,HisB4,GluB10,HisB27]insulin in rat liver in vivo.Heparin alters epidermal growth factor metabolism in cultured rat glomerular epithelial cellsATP-dependent desensitization of insulin binding and tyrosine kinase activity of the insulin receptor kinase. The role of endosomal acidification.Epidermal growth factor receptor down-regulation induced by UVA in human keratinocytes does not require the receptor kinase activity.
P2860
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P2860
Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@ast
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@en
type
label
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@ast
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@en
prefLabel
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@ast
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@en
P2093
P2860
P356
P1476
Ligand-mediated internalizatio ...... rowth factor receptor in vivo.
@en
P2093
Bergeron JJ
Cameron PH
Doherty JJ 2nd
P2860
P304
P356
10.1083/JCB.109.6.2741
P407
P433
P577
1989-12-01T00:00:00Z