Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.
about
Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan AfricansCanonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C.Maternal KIR in combination with paternal HLA-C2 regulate human birth weight.Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemiaHuman NK cells maintain licensing status and are subject to killer immunoglobulin-like receptor (KIR) and KIR-ligand inhibition following ex vivo expansionKIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.The role of the maternal immune system in the regulation of human birthweight.A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia.Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer PopulationKIR3DS1-Specific D0 Domain Polymorphisms Disrupt KIR3DL1 Surface Expression and HLA Binding.Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.KIR and HLA Genotypes Implicated in Reduced Killer Lymphocytes Immunity Are Associated with Vogt-Koyanagi-Harada Disease.Natural killer cell inhibitory receptor expression in humans and mice: a closer look.Direct binding to antigen-coated beads refines the specificity and cross-reactivity of four monoclonal antibodies that recognize polymorphic epitopes of HLA class I moleculesDiagnostic and Biological Significance of KIR Expression Profile Determined by RNA-Seq in Natural Killer/T-Cell Lymphoma.The yin-yang of KIR3DL1/S1: molecular mechanisms and cellular function.Genetic and environmental determinants of human NK cell diversity revealed by mass cytometryDeciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology.Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution.Uterine NK cells: active regulators at the maternal-fetal interface.The early days of NK cells: an example of how a phenomenon led to detection of a novel immune receptor system - lessons from a rat modelSurveillance of cell and tissue perturbation by receptors in the LRC.Co-evolution of MHC class I and variable NK cell receptors in placental mammals.Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction.HIV-1 adaptation to NK cell-mediated immune pressure.KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans.The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay.Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 controlThe role of KIR and HLA interactions in pregnancy complications.Missing or altered self: human NK cell receptors that recognize HLA-C.Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity.Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?Association of the genetic diversity of killer cell immunoglobulin-like receptor genes and HLA-C ligand in Saudi women with breast cancer.KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV.The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3.Production of Recombinant Killer Immunoglobulin-Like Receptors for Crystallography and Luminex-Based Assays.Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.
P2860
Q28534758-BA535843-C34C-4526-9BD1-70CF6CA19C6CQ30252783-22DA6E71-E681-41B4-BDD2-1821B9849116Q33638193-5319BB28-ADAE-4F30-9840-64580DF56D67Q33651178-466EBEBC-33E4-43D4-8FDE-241E3075E757Q33816097-B48CB620-9B92-49B3-A67F-846F999F8CB6Q34345310-AF50F460-81F9-4D2D-A3D9-FA83E526C7E6Q35008470-FD9CE533-E0A9-46C2-9A3F-382E4EA3B9AFQ35031374-98F0DAA4-D648-4C2B-8ACF-11596670AB24Q35751442-2F4C30FA-39C8-4B2F-AE3B-0EED2ED22539Q35864564-2571D72C-4D46-4600-9D60-5EE0B4C8F5F8Q36075234-B8A24B95-9C36-4D10-A6E8-6D11B8ED6B1DQ36094774-A275477E-6CB0-42C9-9FAD-63884FBB9F4CQ36715233-4523356C-238F-4DF9-979F-B15085661423Q36736384-FB4887AB-4B94-415A-9FC2-58C0CDB2D352Q36990211-70A808DD-01A8-4A36-8BE3-89813F36431DQ37090540-03BD5B49-881D-4762-A6F4-A42CAA0CD75EQ37569278-B96FD193-D285-4DFB-A823-7F751C4E2CFFQ37622486-83BC36C4-3FA5-486B-9F57-F66B69B2B899Q37641722-D6B34F81-65E2-4F47-A45B-DB9CA08CB85CQ37726609-D7A56828-10C9-4520-8B8E-6C51511BB985Q38225120-A7B1B1F8-1C05-4E21-9F08-3DB64526D288Q38568867-31C2FD3B-32FD-4AB6-81FD-8767E079ADD3Q38568889-B37A986B-0422-4CE3-9E42-3478C7F83D9FQ38568891-F8A2A4D5-8446-4BCD-A253-C744FCB0F2EBQ38743267-95F2B8D2-A2D8-400E-B94A-816129F33361Q38849746-46FFDEAE-ADF6-4C5C-9EC9-D2E5BC459ED9Q38861402-83163FF2-7B63-4F4D-A9E4-17DE1A2F1423Q39208685-60185B54-DF5A-40E9-ADBA-8EAD49D0ABDEQ39427554-A68C9ACA-60A8-4B9E-BC33-F3FE4749283AQ39427580-E9CA5B91-15CF-46E3-B690-BF2C8E41A650Q40052007-EBCFFC8C-C2FA-4A96-A92F-676E1DC5FE77Q40097257-3F5E518B-B33B-4BFA-B755-605555C9ADFDQ40580231-75687033-A28C-42C2-BC90-873088D87B2EQ40760920-ABC8FDBC-80B9-430B-AAF6-4A8765C053BBQ41016803-16402969-30B8-431C-942A-95F7C2BAFE75Q41731150-7FB1C602-A773-4A37-BCBA-3CE3280D5D20Q47555585-89B4F64A-8C72-411B-93B2-261FCBB0D3F4Q48311471-2217F385-0662-4879-A07A-FD6E7390183FQ51146989-DD00994D-5C57-4A76-8638-AD043D456BBF
P2860
Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@ast
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@en
type
label
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@ast
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@en
prefLabel
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@ast
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@en
P2093
P2860
P356
P1476
Mutation at positively selecte ...... NK cell receptor than KIR2DL3.
@en
P2093
Achim K Moesta
Anastazia M Older Aguilar
Hugo G Hilton
Katharina Fleischhauer
Laurent Abi-Rached
Lisbeth A Guethlein
Peter Parham
Thorsten Graef
P2860
P304
P356
10.4049/JIMMUNOL.1100431
P407
P577
2012-07-06T00:00:00Z