Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. - Wikidata - wikimedia - TriplyDB

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.

http://www.wikidata.org/entity/Q36228950

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Adoptive T cell therapy for cancer in the clinic Emerging therapeutic targets in esophageal adenocarcinoma Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma Immunotherapy for advanced gastric and esophageal cancer: preclinical rationale and ongoing clinical investigations Molecular and clinical implementations of ovarian cancer mouse avatar models The impact of the myeloid response to radiation therapy Combining radiation and immunotherapy: a new systemic therapy for solid tumors?Radiation as immunomodulator: implications for dendritic cell-based immunotherapy Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice Serial low doses of sorafenib enhance therapeutic efficacy of adoptive T cell therapy in a murine model by improving tumor microenvironment Rationale for a Multimodality Strategy to Enhance the Efficacy of Dendritic Cell-Based Cancer Immunotherapy.Immunity, Inflammation, and Cancer The promise of PD-1 inhibitors in gastro-esophageal cancers: microsatellite instability vs. PD-L1 Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells A vaccine that co-targets tumor cells and cancer associated fibroblasts results in enhanced antitumor activity by inducing antigen spreading Immunologic correlates of the abscopal effect in a patient with melanoma The role of local ablative therapy in oligometastatic non-small-cell lung cancer: hype or hope.MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer.Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity Tumor masses support naive T cell infiltration, activation, and differentiation into effectors Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.Engineering higher affinity T cell receptors using a T cell display system.Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions CCL21 and IFNγ recruit and activate tumor specific T cells in 3D scaffold model of breast cancer.Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Single vs. combination immunotherapeutic strategies for glioma.High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics.Towards a genetic definition of cancer-associated inflammation: role of the IDO pathway Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.A randomized controlled trial to investigate the influence of low dose radiotherapy on immune stimulatory effects in liver metastases of colorectal cancer.Targeting immune suppressing myeloid-derived suppressor cells in oncology.Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts Redirecting the immune response: role of adoptive T cell therapy.Radical irradiation of extracranial oligometastases.Rapid accumulation of adoptively transferred CD8+ T cells at the tumor site is associated with long-term control of SV40 T antigen-induced tumors.Bystander killing of cancer requires the cooperation of CD4(+) and CD8(+) T cells during the effector phase.Myxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor activity

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Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.

http://www.wikidata.org/entity/Q36228950

description

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Induced sensitization of tumor ...... established cancer by T cells.

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Induced sensitization of tumor ...... established cancer by T cells.

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Induced sensitization of tumor ...... established cancer by T cells.

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Induced sensitization of tumor ...... established cancer by T cells.

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Induced sensitization of tumor ...... established cancer by T cells.

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Journal of Experimental Medicine

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Induced sensitization of tumor ...... established cancer by T cells.

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Andrea Schietinger

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Bin Zhang

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David M Kranz

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Donald A Rowley

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Hank Schmidt

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Hans Schreiber

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Joseph K Salama

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Michael T Spiotto

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Natalie A Bowerman

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Ping Yu

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P2860

Adoptive immunotherapy for cancer: building on success

Cancer regression in patients after transfer of genetically engineered lymphocytes

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer

TCRs with high affinity for foreign pMHC show self-reactivity.

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy.

The role of tumor stroma in the interaction between tumor and immune system.

Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells

Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis.

Combining radiotherapy and immunotherapy: a revived partnership.

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49-55

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10.1084/JEM.20062056

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1

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204

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Ralph Weichselbaum

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6590096

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17210731

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2118433

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