Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation.
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Specificity of amyloid precursor-like protein 2 interactions with MHC class I moleculesCrystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulationPorcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic.A comparison of viral immune escape strategies targeting the MHC class I assembly pathway.An endoplasmic reticulum-targeting signal sequence enhances the immunogenicity of an immunorecessive simian virus 40 large T antigen cytotoxic T-lymphocyte epitope.The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICBProlonged survival of pancreatic islet allografts mediated by adenovirus immunoregulatory transgenes.The endoplasmic reticulum lumenal domain of the adenovirus type 2 E3-19K protein binds to peptide-filled and peptide-deficient HLA-A*1101 molecules.Control of MHC class I traffic from the endoplasmic reticulum by cellular chaperones and viral anti-chaperones.Determinants of the endoplasmic reticulum (ER) lumenal-domain of the adenovirus serotype 2 E3-19K protein for association with and ER-retention of major histocompatibility complex class I moleculesA short isoform of human cytomegalovirus US3 functions as a dominant negative inhibitor of the full-length form.Adenovirus E3-19K proteins of different serotypes and subgroups have similar, yet distinct, immunomodulatory functions toward major histocompatibility class I moleculesImpairment of monocytic function after influenza virus infectionFunctions and mechanisms of action of the adenovirus E3 proteins.Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver.The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization.Modulation of the antigen transport machinery TAP by friends and enemies.Class I molecules retained in the endoplasmic reticulum bind antigenic peptidesTAP-independent, beta 2-microglobulin-dependent surface expression of functional mouse CD1.1.Deletion mutation analysis of the adenovirus type 2 E3-gp19K protein: identification of sequences within the endoplasmic reticulum lumenal domain that are required for class I antigen binding and protection from adenovirus-specific cytotoxic T lymphDefective major histocompatibility complex class I expression in a sarcomatoid renal cell carcinoma cell line.Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway.Homologous recombination in E3 genes of human adenovirus species DTumor necrosis factor alpha stimulates expression of adenovirus early region 3 proteins: implications for viral persistence.Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens.Role of the adenovirus E3-19k conserved region in binding major histocompatibility complex class I molecules.The amyloid precursor-like protein 2 and the adenoviral E3/19K protein both bind to a conformational site on H-2Kd and regulate H-2Kd expression.Structural and functional dissection of human cytomegalovirus US3 in binding major histocompatibility complex class I molecules.Verapamil enhances the antitumoral efficacy of oncolytic adenoviruses.Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.Lack of effect of mouse adenovirus type 1 infection on cell surface expression of major histocompatibility complex class I antigens.Human adenovirus-specific CD8+ T-cell responses are not inhibited by E3-19K in the presence of gamma interferonDown-regulation of HLA antigens by the adenovirus type 2 E3/19K protein in a T-lymphoma cell line.The transmembrane domain of the adenovirus E3/19K protein acts as an endoplasmic reticulum retention signal and contributes to intracellular sequestration of major histocompatibility complex class I molecules.Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition.Two distinct transport motifs in the adenovirus E3/10.4-14.5 proteins act in concert to down-modulate apoptosis receptors and the epidermal growth factor receptor.Novel proteins associated with MHC class I antigens in cells expressing the adenovirus protein E3/19K.The amyloid precursor-like protein 2 associates with the major histocompatibility complex class I molecule K(d).Tumor necrosis factor alpha induces the adenovirus early 3 promoter by activation of NF-kappaB.Molecular basis of immune evasion strategies by adenoviruses.
P2860
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P2860
Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Retention of adenovirus E19 gl ...... to block antigen presentation.
@ast
Retention of adenovirus E19 gl ...... to block antigen presentation.
@en
type
label
Retention of adenovirus E19 gl ...... to block antigen presentation.
@ast
Retention of adenovirus E19 gl ...... to block antigen presentation.
@en
prefLabel
Retention of adenovirus E19 gl ...... to block antigen presentation.
@ast
Retention of adenovirus E19 gl ...... to block antigen presentation.
@en
P2093
P2860
P356
P1476
Retention of adenovirus E19 gl ...... to block antigen presentation.
@en
P2093
P2860
P304
P356
10.1084/JEM.174.6.1629
P407
P577
1991-12-01T00:00:00Z