Improving on nature: antibiotics that target the ribosome.
about
Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesisPentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translationAntibiotics that target protein synthesisNegamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal SubunitStructural basis for hygromycin B inhibition of protein biosynthesisDiscovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetaseRecent developments in antibacterial drug discovery: microbe-derived natural products--from collection to the clinic.Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR.Discovery and analysis of 4H-pyridopyrimidines, a class of selective bacterial protein synthesis inhibitors.Probing translation with small-molecule inhibitorsFRET enabled real time detection of RNA-small molecule binding.Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites.Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10.Association of antibiotic resistance in agricultural Escherichia coli isolates with attachment to quartz.Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs.Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa.Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteriaChemical biology at the crossroads of molecular structure and mechanism.Antibiotics and the ribosome.Aqueous Glycosylation of Unprotected Sucrose Employing Glycosyl Fluorides in the Presence of Calcium Ion and Trimethylamine.Focused functional dynamics of supramolecules by use of a mixed-resolution elastic network model.Microbiological profile of a new topical antibacterial: retapamulin ointment 1%.Therapeutics based on stop codon readthrough.Strategies for the design of RNA-binding small molecules.Riboswitch-based antibacterial drug discovery using high-throughput screening methods.Use of RNA in drug design.Designing drugs that overcome antibacterial resistance: where do we stand and what should we do?Antimicrobial aptamers for detection and inhibition of microbial pathogen growth.The use of aminoglycoside derivatives to study the mechanism of aminoglycoside 6'-N-acetyltransferase and the role of 6'-NH2 in antibacterial activityEffective in silico prediction of new oxazolidinone antibiotics: force field simulations of the antibiotic-ribosome complex supervised by experiment and electronic structure methods.Defining the RNA-protein interactions in the trypanosome preribosomal complex.Impairment of ribosomal subunit synthesis in aminoglycoside-treated ribonuclease mutants of Escherichia coli.Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells.
P2860
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P2860
Improving on nature: antibiotics that target the ribosome.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Improving on nature: antibiotics that target the ribosome.
@ast
Improving on nature: antibiotics that target the ribosome.
@en
type
label
Improving on nature: antibiotics that target the ribosome.
@ast
Improving on nature: antibiotics that target the ribosome.
@en
prefLabel
Improving on nature: antibiotics that target the ribosome.
@ast
Improving on nature: antibiotics that target the ribosome.
@en
P1476
Improving on nature: antibiotics that target the ribosome.
@en
P2093
Joyce A Sutcliffe
P304
P356
10.1016/J.MIB.2005.08.004
P577
2005-10-01T00:00:00Z