Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product
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Main roads to melanomaMelanoma: from melanocyte to genetic alterations and clinical optionsPhospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expressionBrachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter.Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmiaThe gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytesOTX2 activates the molecular network underlying retina pigment epithelium differentiationMicrophthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transportA polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathwayEffects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidumTargeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivoMutations of TYR and MITF Genes are Associated with Plumage Colour Phenotypes in Geese.Inhibitory effect of piperlonguminine on melanin production in melanoma B16 cell line by downregulation of tyrosinase expression.The murine misty mutation: phenotypic effects on melanocytes, platelets and brown fatCtBP2 downregulation during neural crest specification induces expression of Mitf and REST, resulting in melanocyte differentiation and sympathoadrenal lineage suppression.Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth.Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival.c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.Activation of the long terminal repeat of human endogenous retrovirus K by melanoma-specific transcription factor MITF-M.cAMP-dependent activation of protein kinase A as a therapeutic target of skin hyperpigmentation by diphenylmethylene hydrazinecarbothioamideSOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentationIdentification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial CellsOcular melanogenesis: the role of antioxidants.N-(4-methoxyphenyl) caffeamide-induced melanogenesis inhibition mechanismsMicrophthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes.Characterization of genes modulated during pheomelanogenesis using differential displayInhibition of Rho is required for cAMP-induced melanoma cell differentiation.Mitogen-activated protein kinase cascade required for regulation of development and secondary metabolism in Neurospora crassa.Inhibition of melanogenesis by gallic acid: possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells.Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.The melanogenesis and mechanisms of skin-lightening agents--existing and new approaches.Involvement of ITF2 in the transcriptional regulation of melanogenic genes.Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy.Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway.CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells.The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.Depigmenting effect of Kojic acid esters in hyperpigmented B16F1 melanoma cells.A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells.
P2860
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P2860
Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
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1996年學術文章
@zh-hant
name
Regulation of tyrosinase gene ...... he microphthalmia gene product
@ast
Regulation of tyrosinase gene ...... he microphthalmia gene product
@en
type
label
Regulation of tyrosinase gene ...... he microphthalmia gene product
@ast
Regulation of tyrosinase gene ...... he microphthalmia gene product
@en
prefLabel
Regulation of tyrosinase gene ...... he microphthalmia gene product
@ast
Regulation of tyrosinase gene ...... he microphthalmia gene product
@en
P2093
P2860
P356
P1476
Regulation of tyrosinase gene ...... he microphthalmia gene product
@en
P2093
Ballotti R
Bertolotto C
Ortonne JP
P2860
P304
P356
10.1083/JCB.134.3.747
P407
P577
1996-08-01T00:00:00Z