Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.
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Impaired T-Cell Function in B-Cell Lymphoma: A Direct Consequence of Events at the Immunological Synapse?The SCHOOL of nature: I. Transmembrane signaling.Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice.Re-adapting T cells for cancer therapy: from mouse models to clinical trials.Mechanism of T cell tolerance induced by myeloid-derived suppressor cells.Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceAbrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.Self-tolerance checkpoints in CD4 T cells specific for a peptide derived from the B cell antigen receptor.Genetically retargeting CD8+ lymphocyte subsets for cancer immunotherapy.Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome.Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivoDurable adoptive immunotherapy for leukemia produced by manipulation of multiple regulatory pathways of CD8+ T-cell tolerance.CD8+ T cell exhaustion during persistent viral infection is regulated independently of the virus-specific T cell receptor.GILT: Shaping the MHC Class II-Restricted Peptidome and CD4(+) T Cell-Mediated Immunity.Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells.Heterogeneity assessment of functional T cell avidity.Enhanced T cell receptor gene therapy for cancer.Progress and prospects: graft-versus-host disease.Tolerance and exhaustion: defining mechanisms of T cell dysfunction.Self-reactivity as the necessary cost of maintaining a diverse memory T-cell repertoire.Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains.Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.Adoptive immunotherapy of disseminated leukemia with TCR-transduced, CD8+ T cells expressing a known endogenous TCR.Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state.Rescue of Tolerant CD8+ T Cells during Cancer Immunotherapy with IL2:Antibody Complexes.APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice.Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis.
P2860
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P2860
Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@ast
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@en
type
label
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@ast
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@en
prefLabel
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@ast
Peripheral CD8+ T cell toleran ...... imally at the T cell receptor.
@en
P2093
P2860
P1433
P1476
Peripheral CD8+ T cell toleran ...... ximally at the T cell receptor
@en
P2093
Carla Fowler
Claes Ohlén
Eric S Huseby
Junko Morimoto
Michelle L Dossett
Philip D Greenberg
Ryan M Teague
Xiaoxia Tan
P2860
P304
P356
10.1016/J.IMMUNI.2008.03.012
P407
P577
2008-05-01T00:00:00Z