Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback
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Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cellsThe Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid ArthritisCotransfer of regulatory T cells improve the therapeutic effectiveness of mesenchymal stem cells in treating a colitis mouse modelPotent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction--a novel mechanism for maintaining vascular functionDectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markersAn important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) miceThe JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis.Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of TuberculosisDifferential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophagesTreatment of Experimental Candida Sepsis with a Janus Kinase Inhibitor Controls Inflammation and Prolongs SurvivalMSK1 and MSK2 inhibit lipopolysaccharide-induced prostaglandin production via an interleukin-10 feedback loopOTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages.Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathwaysIL-6-mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages.Essential role of IL-10/STAT3 in chronic stress-induced immune suppression.Specific therapy to regulate inflammation in rheumatoid arthritis: molecular aspects.The role of the mediators of inflammation in cancer development.Upcoming Therapeutic Targets in Cutaneous Lupus Erythematous.Development of Selective Covalent Janus Kinase 3 Inhibitors.Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases.Regulation of Interleukin-10 Expression.IL-10: A Multifunctional Cytokine in Viral Infections.PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.Beta Interferon Production Is Regulated by p38 Mitogen-Activated Protein Kinase in Macrophages via both MSK1/2- and Tristetraprolin-Dependent Pathways.Computational identification and analysis of signaling subnetworks with distinct functional roles in the regulation of TNF production.Fungal pattern receptors down-regulate the inflammatory response by a cross-inhibitory mechanism independent of interleukin-10 production.MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages.Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation.miR-27a regulates inflammatory response of macrophages by targeting IL-10.Induction of human IL-10-producing neutrophils by LPS-stimulated Treg cells and IL-10.JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms.Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages.STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.Chemical JAK inhibitors for the treatment of rheumatoid arthritis.LEE011 and ruxolitinib: a synergistic drug combination for natural killer/T-cell lymphoma (NKTCL)
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P2860
Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@ast
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@en
type
label
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@ast
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@en
prefLabel
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@ast
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@en
P2860
P356
P1476
Inhibition of JAKs in macropha ...... ocking IL-10-mediated feedback
@en
P2093
Kirsty F Mackenzie
P2860
P304
P356
10.4049/JIMMUNOL.1200310
P407
P577
2012-08-17T00:00:00Z