RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. - Wikidata - wikimedia - TriplyDB

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation.

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation.

http://www.wikidata.org/entity/Q36238093

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Genetic abnormalities associated with acute lymphoblastic leukemia Specification and function of hemogenic endothelium during embryogenesis Identification of a novel retinoid by small molecule screening with zebrafish embryos Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse Minireview: Nuclear receptors, hematopoiesis, and stem cells.Gene expression patterns in myelodyplasia underline the role of apoptosis and differentiation in disease initiation and progression.High aldehyde dehydrogenase activity: a novel functional marker of murine prostate stem/progenitor cells Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.Inhibiting vitamin A metabolism as an approach to male contraception.RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes.Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.Retinoic acid regulates hematopoietic development from human pluripotent stem cells ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells.Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.Cancer stem cells: potential target for bioactive food components Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation.A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency.Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance.Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure.Spermatogenesis: The Commitment to Meiosis.BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells.Stem-cell ecology and stem cells in motion RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells Retinoic acid decreases adherence of murine myeloid dendritic cells and increases production of matrix metalloproteinase-9.Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis.Retinoids accelerate B lineage lymphoid differentiation Control of adult stem cells in vivo by a dynamic physiological environment: diet-dependent systemic factors in Drosophila and beyond.Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture.Pathways of retinoid synthesis in mouse macrophages and bone marrow cells Oncogenic activity of retinoic acid receptor γ is exhibited through activation of the Akt/NF-κB and Wnt/β-catenin pathways in cholangiocarcinoma.A unique cytoplasmic localization of retinoic acid receptor-gamma and its regulations Nuclear receptor regulation of stemness and stem cell differentiation.Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality.Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity.

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P2860

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation.

http://www.wikidata.org/entity/Q36238093

description

2006 nî lūn-bûn

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2006年の論文

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RARgamma is critical for maint ...... f-renewal and differentiation.

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RARgamma is critical for maint ...... f-renewal and differentiation.

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RARgamma is critical for maint ...... f-renewal and differentiation.

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RARgamma is critical for maint ...... f-renewal and differentiation.

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RARgamma is critical for maint ...... f-renewal and differentiation.

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RARgamma is critical for maint ...... f-renewal and differentiation.

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Gemma Haines Olsen

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Steven J Collins

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Stewart A Fabb

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P2860

Molecular pathogenesis of acute promyelocytic leukaemia and APL variants

Signalling downstream of activated mammalian Notch

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

Function of retinoic acid receptor gamma in the mouse

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice

Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells

A role for Wnt signalling in self-renewal of haematopoietic stem cells

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

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1283-1293

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10.1084/JEM.20052105

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203

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Sebastian Dworkin

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7099599

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2121209

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