Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
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The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesisAraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production.Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitorsReduction of lattice disorder in protein crystals by high-pressure cryocooling.Ribosome•RelA structures reveal the mechanism of stringent response activation.The stringent response regulates adaptation to darkness in the cyanobacterium Synechococcus elongatus.Computational method allowing Hydrogen-Deuterium Exchange Mass Spectrometry at single amide Resolution.The magic dance of the alarmones (p)ppGpp.Small Alarmone Synthetases as novel bacterial RNA-binding proteins.Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.Identification and Functional Characterization of Small Alarmone Synthetases in Corynebacterium glutamicumStructural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ.The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.Functional Characterization of a Small Alarmone Hydrolase in Corynebacterium glutamicum.Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA.Regulation of the opposing (p)ppGpp synthetase and hydrolase activities in a bifunctional RelA/SpoT homologue from Staphylococcus aureus
P2860
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P2860
Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@ast
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@en
type
label
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@ast
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@en
prefLabel
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@ast
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@en
P2093
P2860
P356
P1476
Catalytic mechanism and allost ...... Gpp synthetase by an alarmone.
@en
P2093
Florian Altegoer
Jan S Schuhmacher
Mohamed A Marahiel
Vasundara Srinivasan
Wieland Steinchen
P2860
P304
13348-13353
P356
10.1073/PNAS.1505271112
P407
P577
2015-10-12T00:00:00Z