The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.
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APE1/Ref-1 regulates PTEN expression mediated by Egr-1Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1Hallmarks of cancer and AU-rich elementsThe progress of early growth response factor 1 and leukemiaSteering tumor progression through the transcriptional response to growth factors and stromaDisease progression mediated by egr-1 associated signaling in response to oxidative stressNAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathwayDCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinomaTherapy-related myeloid neoplasms: pathobiology and clinical characteristicsEarly growth response 1 (Egr-1) regulates phosphorylation of microtubule-associated protein tau in mammalian brainEarly growth response-1 transcription factor promotes hepatic fibrosis and steatosis in long-term ethanol-fed Long-Evans ratsCDK6 as a key regulator of hematopoietic and leukemic stem cell activationThe Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1Genetic variants on chromosome 1q41 influence ocular axial length and high myopiaCavin-3 dictates the balance between ERK and Akt signaling.Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein.Identification of egr1 direct target genes in the uterus by in silico analyses with expression profiles from mRNA microarray dataCoordinated sumoylation and ubiquitination modulate EGF induced EGR1 expression and stability.Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells.Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders.A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survivalAnalysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection.The many functions of APE1/Ref-1: not only a DNA repair enzymeAssociation of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells.Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors.Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1.Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer.EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression.Haploinsufficient tumor suppressor genes.Chlorpromazine activates p21Waf1/Cip1 gene transcription via early growth response-1 (Egr-1) in C6 glioma cells.Androgen deprivation therapy induces androgen receptor-dependent upregulation of Egr1 in prostate cancers.Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells.Quantifying differential gene connectivity between disease states for objective identification of disease-relevant genes.Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks.Heparin inhibits Hepatocyte Growth Factor induced motility and invasion of hepatocellular carcinoma cells through early growth response protein 1.Transcriptional regulation of flotillins by the extracellularly regulated kinases and retinoid X receptor complexes.An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-RasMet-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotypeSensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression.
P2860
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P2860
The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@ast
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@en
type
label
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@ast
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@en
prefLabel
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@ast
The transcription factor Egr1 ...... 1, PTEN, p53, and fibronectin.
@en
P2093
P2860
P356
P1433
P1476
The transcription factor Egr1 ...... a1, PTEN, p53, and fibronectin
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.CGT.7700896
P577
2006-02-01T00:00:00Z