Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate.
about
ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranesProtein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signallingPhospholipase D: molecular and cell biology of a novel gene familyDetermination of interaction sites of phospholipase D1 for RhoAStructure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nucleaseThe tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamilymRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral ResearchMechanism of enzymatic reaction and protein-protein interactions of PLD from a 3D structural model.The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesisStructure and function of Zucchini endoribonuclease in piRNA biogenesisMutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathyPhospholipase DRecognition of phospholipids in Streptomyces phospholipase D.Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis.Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase.Requirements and effects of palmitoylation of rat PLD1.Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model.Design, synthesis, and biological evaluation of O-2-modified indenoisoquinolines as dual topoisomerase I-tyrosyl-DNA phosphodiesterase I inhibitors.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerHuman Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.Attempting to rewrite History: challenges with the analysis of histidine-phosphorylated peptides.pHisphorylation: the emergence of histidine phosphorylation as a reversible regulatory modification.Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.Phospholipase D: enzymology, functionality, and chemical modulationSite-specific DNA transesterification catalyzed by a restriction enzyme.Development of a Novel Tetravalent Synthetic Peptide That Binds to Phosphatidic AcidChasing phosphohistidine, an elusive sibling in the phosphoamino acid family.Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyTDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate.Phospholipase D in platelets and other cells.Moraxella catarrhalis expresses a cardiolipin synthase that impacts adherence to human epithelial cells.Nucleases: diversity of structure, function and mechanism.Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Novel subtype of type IIs restriction enzymes. BfiI endonuclease exhibits similarities to the EDTA-resistant nuclease Nuc of Salmonella typhimurium.Mutating His29, His125, His133 or His158 abolishes glycosylphosphatidylinositol-specific phospholipase D catalytic activity.A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active siteExpression, characterization, and mutagenesis of the Yersinia pestis murine toxin, a phospholipase D superfamily member.Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme speciesAssociation of N- and C-terminal domains of phospholipase D is required for catalytic activity.
P2860
Q24300505-0775DD58-6F35-4127-BFD7-517AFAA4A372Q24337871-4168DF2F-B8DD-4D77-9C8E-829E7CBC7ED6Q24531909-A234F7F4-581E-456A-A909-007D9B8F958FQ24532779-42CE9B39-19DC-41AA-B5AE-C0A572365D68Q24535057-FE66F348-DFA3-441A-9887-CECB4E5A1E77Q24555147-FFAC2D3C-D045-4A85-AF9E-466E5EC8DDB3Q24701721-30380D9B-EF53-40C0-9CC4-A86C6C9976CEQ27321589-159787D9-F6C3-4ACA-9B95-90DAD4D7549EQ27674509-58E2AF42-D33E-4752-9D65-9F8AE29440D3Q27682791-FDE4A812-5747-446D-A0B2-31F7317D73E9Q28203189-C214813E-44AD-4BD2-9A9C-97AC09816B1EQ28253553-EBAAAAEF-6340-4A59-A5E8-4673D8FD1B94Q30784356-F8B7EA7D-1CB5-43EA-83F8-1F88DAFDFFFAQ30819575-BA029EEF-70EA-44A0-9ED0-87C6972F2FBEQ31114437-9A0D9342-9089-4DAA-8D83-21BCE1696B30Q31717168-9471D617-18A2-4530-9B8A-E201653CC581Q31795467-F16ECA17-C7B1-4DB8-89E4-9F4E82FEB023Q33662415-1973407A-7CE4-41CF-89AC-E0CEAE2B9739Q34268347-9A64D631-E34F-4D22-A887-3E7D96887F27Q34312801-6FFE9DA5-FF1A-4066-8984-1B546D5F1B6EQ34358051-38FBEB1A-D4AB-4556-9AA5-F4B6148232FCQ34550161-C0C76A14-98C7-4ACB-A906-486BE6E2B4D0Q35152316-44A90BA0-C69C-4C7B-9735-92B36C09C564Q35599714-10F3070A-6049-48DF-AEA3-B7A0A679DBB4Q35616738-836676C8-5498-4D03-B2CF-70B908A35903Q35683934-70776476-5B1D-4031-8963-C4C55F8CB7E3Q35687878-38434CF1-E5C9-4898-B2A0-9587F26C013CQ36744910-0FF95D84-5316-43E1-9A27-BFA0E66EA9C3Q37148469-8BF5BF8C-6D8F-487D-97AC-31B7750DFF10Q37317579-B1C6F018-5518-40FB-BB5D-4765E964F3DCQ37326638-E901D22D-BEA3-4054-B562-2B44515F88FEQ37545605-B68A8AD9-0943-4B24-9F25-3CFE1DFB0795Q37790458-674C301D-D45B-42F3-B49A-9DA50922689FQ38261264-356B0286-E4F9-4A84-99B3-41893DE4FF27Q38310779-4387C594-1D93-4B9A-B358-E4208859DE25Q39498057-DBF0F54C-223A-4878-9CC2-EFDC25A4A885Q39986656-42F3032F-A3BE-4ECB-BC92-8038FD72DE9DQ41483160-55FBB4B0-D559-4CE2-94E6-6D0538067703Q41886523-6BDA73DB-3FC8-48DF-A7C2-5EEFC1640578Q42465463-633358E8-BDDC-4F92-8E5F-FB03FB7A72F5
P2860
Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@ast
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@en
type
label
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@ast
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@en
prefLabel
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@ast
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@en
P2093
P2860
P356
P1476
Catalytic mechanism of the pho ...... phosphohistidine intermediate.
@en
P2093
A E Rudolph
E B Gottlin
H R Matthews
P2860
P304
P356
10.1073/PNAS.95.16.9202
P407
P577
1998-08-01T00:00:00Z